SCHEMBL342810

SCHEMBL342810

COc1ccc(SCC(=O)O)cc1OC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.53
MAPT P10636 5/20 0.50
CTSB P07858 1/20 0.50
ELANE P08246 1/20 0.50
DUSP3 P51452 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
FFAR1 O14842 1/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50
CA7 P43166 1/20 0.50
TPMT P51580 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
GAA P10253 3/20 0.49
APEX1 P27695 1/20 0.49
POLB P06746 1/20 0.48
TRPM5 Q9NZQ8 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10441459 0.88 GAA (0.55) ALDH1A1CTSBELANEDUSP3FFAR1
SCHEMBL9364409 0.88 ALDH1A1 (0.53) ALDH1A1MAPTCTSBELANEDUSP3
SCHEMBL16492192 0.87 GRK6 (0.49) ALDH1A1MAPTCTSBELANEDUSP3
SCHEMBL3480452 0.83 SMN1; SMN2 (0.48) ALDH1A1MAPTSMN1; SMN2CA12CA1
SCHEMBL8471824 0.83 NPC1 (0.55) ALDH1A1MAPTSMN1; SMN2CA12CA1
SCHEMBL2499200 0.82 MAPT (0.60) ALDH1A1MAPTSMN1; SMN2GAAPOLB
SCHEMBL10335474 0.80 ALDH1A1 (0.56) ALDH1A1MAPTSMN1; SMN2CA12CA1
SCHEMBL28754525 0.80 GAA (0.54) ALDH1A1MAPTGAAPOLBCYP1A2
SCHEMBL9463343 0.79 TSHR (0.53) ALDH1A1CTSBELANEDUSP3FFAR1
SCHEMBL6823193 0.79 NPC1 (0.58) ALDH1A1MAPTSMN1; SMN2CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090246700-A1 PLATE-MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-10-01 US claimed
EP-1497122-B1 STABILIZED INFRARED-SENSITIVE POLYMERIZABLE SYSTEMS KODAK POLYCHROME GRAPHICS GMBH (DE) 2006-05-31 EP claimed
EP-1539492-B1 HIGH SPEED NEGATIVE-WORKING THERMAL PRINTING PLATES KODAK POLYCHROME GRAPHICS LLC (US) 2006-05-17 EP claimed
EP-1556227-A1 HETERO-SUBSTITUTED ARYL ACETIC ACID CO-INITIATORS FOR IR-SENSITIVE COMPOSITIONS Kodak Polychrome Graphics LLC (US) 2005-07-27 EP claimed
EP-1539492-A1 HIGH SPEED NEGATIVE-WORKING THERMAL PRINTING PLATES Kodak Polychrome Graphics, LLC (US) 2005-06-15 EP claimed
US-6899992-B2 Polymerizable compounds with quadruple hydrogen bond forming groups KODAK POLYCHROME GRAPHICS LLC (US) 2005-05-31 US claimed
US-6893797-B2 High speed negative-working thermal printing plates KODAK POLYCHROME GRAPHICS LLC (US) 2005-05-17 US claimed
US-6884568-B2 Stabilized infrared-sensitive polymerizable systems KODAK POLYCHROME GRAPHICS, LLC (US) 2005-04-26 US claimed
EP-1497122-A1 STABILIZED INFRARED-SENSITIVE POLYMERIZABLE SYSTEMS Kodak Polychrome Graphics GmbH (DE) 2005-01-19 EP claimed
WO-2004041544-A1 HETERO-SUBSTITUTED ARYL ACETIC ACID CO-INITIATORS FOR IR-SENSITIVE COMPOSITIONS KODAK POLYCHROME GRAPHICS LLC (US) 2004-05-21 WO claimed
US-20040091811-A1 Hetero-substituted aryl acetic acid co-initiators for IR-sensitive compositions KODAK POLYCHROME GRAPHICS, LLC 2004-05-13 US claimed
US-20040091812-A1 Polymerizable compounds with quadruple hydrogen bond forming groups KODAK AMERICAS LTD. 2004-05-13 US claimed
WO-2004014652-A1 HIGH SPEED NEGATIVE-WORKING THERMAL PRINTING PLATES KODAK POLYCHROME GRAPHICS LLC (US) 2004-02-19 WO claimed
WO-2003091022-A1 STABILIZED INFRARED-SENSITIVE POLYMERIZABLE SYSTEMS KODAK POLYCHROME GRAPHICS GMBH (DE) 2003-11-06 WO claimed
US-20030124460-A1 High speed negative-working thermal printing plates KODAK PHILIPPINES LTD. 2003-07-03 US claimed
US-20020197564-A1 Stabilized infrared-sensitive polymerizable systems KODAK AMERICAS LTD. 2002-12-26 US claimed
CN-114591312-B Sulfone and sulfoxide compounds, preparation method and medical application thereof 中国药科大学 2023-07-28 CN disclosed
CN-114591312-A Sulfone and sulfoxide compounds, preparation method and medical application thereof 中国药科大学 2022-06-07 CN disclosed
EP-0635018-A1 4-(1H-2-METHYLIMIDAZO 4,5-c]PYRIDINYLMETHYL)PHENYLSULPHONAMIDE DERIVATIVES AS ANTAGONISTS OF PAF BRITISH BIO-TECHNOLOGY LIMITED (GB) 1995-01-25 EP disclosed
WO-1993016075-A1 4-(1H-2-METHYLIMIDAZO[4,5-c]PYRIDINYLMETHYL)PHENYLSULPHONAMIDE DERIVATIVES AS ANTAGONISTS OF PAF BRITISH BIO-TECHNOLOGY LIMITED (GB) 1993-08-19 WO disclosed