Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | GRK6 | P43250 | 5/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL342810 | 0.88 | ALDH1A1 (0.53) | ALDH1A1MAPTLMNARXFP1CTSB | |
| SCHEMBL9360064 | 0.85 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNARXFP1PPARD | |
| SCHEMBL9360247 | 0.84 | ALDH1A1 (0.50) | ALDH1A1MAPTLMNAPPARDCTSB | |
| SCHEMBL9365316 | 0.81 | NCEH1 (0.47) | ALDH1A1LMNACTSBELANEDUSP3 | |
| SCHEMBL10441459 | 0.81 | GAA (0.55) | ALDH1A1CTSBELANEDUSP3FFAR1 | |
| SCHEMBL9862895 | 0.80 | POLB (0.48) | ALDH1A1PPARDFFAR1GAASMN1; SMN2 | |
| SCHEMBL9360631 | 0.80 | ALDH1A1 (0.55) | ALDH1A1MAPTLMNARXFP1CTSB | |
| SCHEMBL16492192 | 0.79 | GRK6 (0.49) | ALDH1A1MAPTPPARDCTSBELANE | |
| SCHEMBL9360274 | 0.79 | ALDH1A1 (0.44) | ALDH1A1MAPTLMNAPPARDCTSB | |
| SCHEMBL1420805 | 0.78 | ANPEP (0.67) | ALDH1A1MAPTLMNARXFP1CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0419676-B1 | THIONAPHTHALENE DERIVATIVES, METHOD OF PRODUCING THE SAME, AND ANTIALLERGIC AGENT CONTAINING THE SAME | TEIJIN LTD (JP) | 1994-12-07 | — | — | EP | disclosed |
| EP-0419676-A1 | THIONAPHTHALENE DERIVATIVES, METHOD OF PRODUCING THE SAME, AND ANTIALLERGIC AGENT CONTAINING THE SAME | TEIJIN LIMITED (JP) | 1991-04-03 | — | — | EP | disclosed |