Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.44 |
| ▸ | FEN1 | P39748 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylether SCHEMBL896890 | 0.85 | LTA4H (0.55) | LTA4HAKR1C3ERCC5FEN1TSHR | |
| Diphenylether SCHEMBL55934 | 0.81 | LTA4H (0.47) | LTA4HAKR1C3ERCC5FEN1TSHR | |
| Diphenylether SCHEMBL1001110 | 0.79 | LTA4H (0.52) | LTA4HTSHRSMN1; SMN2FFAR1RECQL | |
| Diphenylether SCHEMBL896406 | 0.79 | LTA4H (0.52) | LTA4HTSHRSMN1; SMN2FFAR1RECQL | |
| Diphenylether SCHEMBL5275954 | 0.79 | LTA4H (0.52) | LTA4HTSHRSMN1; SMN2FFAR1RECQL | |
| Diphenylether SCHEMBL27801863 | 0.78 | LTA4H (0.63) | LTA4HTSHRSMN1; SMN2FFAR1PARP10 | |
| Diphenylether SCHEMBL8837235 | 0.78 | LTA4H (0.71) | LTA4HTSHRFFAR1PARP10SRD5A2 | |
| Diphenylether SCHEMBL51188 | 0.78 | LTA4H (0.71) | LTA4HTSHRFFAR1PARP10SRD5A2 | |
| Ethylene Glycol SCHEMBL7048051 | 0.78 | PTGS1 (0.36) | AKR1C3MAPT | |
| Ethylene Glycol SCHEMBL900884 | 0.78 | PTGS1 (0.36) | AKR1C3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247747-A2 | CELL CULTURE ARTICLE AND SCREENING | Geron Corporation (US) | 2010-11-10 | — | — | EP | disclosed |
| WO-2009099552-A2 | CELL CULTURE ARTICLE AND SCREENING | CORNING INCORPORATED (US) | 2009-08-13 | — | — | WO | disclosed |