Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | RPA1 | P27694 | 2/20 | 0.47 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.44 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | PPP1CA | P62136 | 3/20 | 0.44 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.44 |
| ▸ | FABP3 | P05413 | 2/20 | 0.44 |
| ▸ | FABP4 | P15090 | 2/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 2/20 | 0.42 |
| ▸ | RXRB | P28702 | 2/20 | 0.42 |
| ▸ | RXRG | P48443 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3430105 | 0.92 | KMT2A (0.54) | MEN1KMT2AATMRPA1PTGS2 | |
| SCHEMBL3431022 | 0.90 | RPA1 (0.47) | MEN1KMT2AATMRPA1PTGS2 | |
| SCHEMBL3430698 | 0.89 | PPP1CA (0.52) | MEN1KMT2AATMSMN1; SMN2RPA1 | |
| SCHEMBL3431908 | 0.88 | KMT2A (0.51) | MEN1KMT2AATMSMN1; SMN2RPA1 | |
| SCHEMBL7156590 | 0.88 | MALT1 (0.58) | MEN1KMT2AATMSMN1; SMN2RPA1 | |
| SCHEMBL3428197 | 0.85 | RXRA (0.52) | MEN1KMT2AATMSMN1; SMN2RPA1 | |
| SCHEMBL3431896 | 0.85 | FAAH (0.47) | MEN1KMT2AATMSMN1; SMN2RPA1 | |
| SCHEMBL3428855 | 0.82 | PPP1CA (0.50) | MEN1KMT2AATML3MBTL1SLC16A3 | |
| SCHEMBL6053701 | 0.82 | RPA1 (0.57) | MEN1KMT2AATMSMN1; SMN2RPA1 | |
| SCHEMBL1765048 | 0.82 | KMT2A (0.75) | MEN1KMT2AATMSMN1; SMN2RPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2254885-A1 | (PYRAZOLYL CARBONYL)IMIDAZOLIDINONE DERIVATIVES FOR THE TREATMENT OF RETROVIRAL DISEASES | AiCuris GmbH & Co. KG (DE) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009115213-A1 | (PYRAZOLYL CARBONYL)IMIDAZOLIDINONE DERIVATIVES FOR THE TREATMENT OF RETROVIRAL DISEASES | AICURIS GMBH & CO. KG (DE) | 2009-09-24 | — | — | WO | disclosed |