SCHEMBL342880

SCHEMBL342880

[CH2]Cc1ccc(CCC)cc1

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LPL P06858 2/20 0.50
LIPG Q9Y5X9 2/20 0.50
THRB P10828 2/20 0.47
CA2 P00918 1/20 0.46
MGLL Q99685 1/20 0.43
PLK1 P53350 1/20 0.43
CNR1 P21554 1/20 0.43
CNR2 P34972 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.41
TAAR1 Q96RJ0 1/20 0.39
POLB P06746 2/20 0.38
CTDSP1 Q9GZU7 2/20 0.38
NISCH Q9Y2I1 1/20 0.38
HTR1D P28221 1/20 0.38
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
GAA P10253 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28886914 0.91 LPL (0.43) LPLLIPGTHRBCA2MGLL
SCHEMBL142480 0.85 LPL (0.62) LPLLIPGTHRBCA2MGLL
SCHEMBL363054 0.84 CA2 (0.54) LPLLIPGTHRBCA2MGLL
SCHEMBL910863 0.83 LPL (0.50) LPLLIPGTHRBCA2MGLL
SCHEMBL1610768 0.83 LPL (0.50) LPLLIPGTHRBCA2MGLL
SCHEMBL1609476 0.82 ESR1 (0.59) LPLLIPGTHRBCA2MGLL
SCHEMBL9839848 0.82 LPL (0.59) LPLLIPGTHRBCA2MGLL
Water SCHEMBL28941509 0.82 LPL (0.59) LPLLIPGTHRBCA2MGLL
SCHEMBL27871086 0.81 LPL (0.48) LPLLIPGTHRBCA2MGLL
SCHEMBL1611473 0.80 ESR1 (0.63) LPLLIPGTHRBMGLLKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 242 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115260834-A Sulfur-containing high-refractive-index ink composition and preparation method thereof 西安思摩威新材料有限公司 2022-11-01 CN claimed
CN-102015651-B Compounds and compositions as TLR activity modulators IRM LLC 2014-12-31 CN claimed
US-8557912-B2 Thermoplastic resin composition CHEIL INDUSTRIES INC. (KR) 2013-10-15 US claimed
CN-102584829-A Pyrazole and pyrazine diketone derivative and application thereof UNIV SHANDONG 2012-07-18 CN claimed
US-20120016068-A1 Thermoplastic Resin Composition CHEIL INDUSTRIES INC. (KR) 2012-01-19 US claimed
CN-101367819-B 5-substituent-2-(4-substituted phenyl)-6,7-dihydrogen pyrazole-[1,5-a]pyrazine-4(5H)-ketone derivant and uses thereof UNIV SHANDONG 2010-08-18 CN claimed
CN-101633675-A Preparation and application of 5-substituent group-6-substituent phenyl-2-ferrocenyl pyrazolo [1, 5-a] pyrazine-4(5H)-ketone derivative UNIV SHANDONG 2010-01-27 CN claimed
CN-101367819-A 5-substituent-2-(4-substituted phenyl)-6,7-dihydrogen pyrazole-[1,5-a]pyrazine-4(5H)-ketone derivant and uses thereof UNIV SHANDONG (CN) 2009-02-18 CN claimed
EP-1177227-B1 WATER PLASTICIZED HIGH REFRACTIVE INDEX POLYMER FOR OPHTHALMIC APPLICATIONS SURGIDEV CORP (US) 2003-10-01 EP claimed
US-20020128417-A1 Water plasticized high refractive index polymer for ophthalmic applications SURGIDEV CORPORATION (US) 2002-09-12 US claimed
EP-1177227-A1 WATER PLASTICIZED HIGH REFRACTIVE INDEX POLYMER FOR OPHTHALMIC APPLICATIONS SURGIDEV CORPORATION (US) 2002-02-06 EP claimed
US-20020007032-A1 Water plasticized high refractive index polymer for ophthalmic applications SURGIDEV CORPORATION (US) 2002-01-17 US claimed
US-20010056165-A1 Water plasticized high refractive index polymer for ophthalmic applications SURGIDEV CORPORATION (US) 2001-12-27 US claimed
US-6281319-B1 HYDRATABLE POLYMER SURGIDEV CORPORATION 2001-08-28 US claimed
WO-2000061646-A1 WATER PLASTICIZED HIGH REFRACTIVE INDEX POLYMER FOR OPHTHALMIC APPLICATIONS SURGIDEV CORPORATION (US) 2000-10-19 WO claimed
EP-1021423-A1 MACROCYCLIC INHIBITORS OF MATRIX METALLOPROTEINASES AND TNF$g(a) SECRETION Abbott Laboratories (US) 2000-07-26 EP claimed
US-5952320-A USEFUL IN THE TREATMENT OF DISEASES IN WHICH MATRIX METALLOPROTEINASE PLAY A ROLE; MATRIX METALLOPROTEINASE INHIBITING COMPOSITIONS ABBOTT LABORATORIES (US) 1999-09-14 US claimed
WO-1998030551-A1 MACROCYCLIC INHIBITORS OF MATRIX METALLOPROTEINASES AND TNFα SECRETION ABBOTT LABORATORIES (US) 1998-07-16 WO claimed
WO-2024122629-A1 DYE FOR DYING USING SUPERCRITICAL CARBON DIOXIDE 紀和化学工業株式会社 2024-06-13 WO disclosed
US-3971825-A (5,6) (10,11) BIS-METHYLENE, BRONCHODILATORS SANKYO COMPANY LIMITED (JA) 1976-07-27 US disclosed