Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 2/20 | 0.50 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27871086 | 0.97 | LPL (0.48) | LPLLIPGTHRBCA2MGLL | |
| SCHEMBL6747631 | 0.93 | LPL (0.45) | LPLLIPGTHRBCA2MGLL | |
| SCHEMBL142480 | 0.85 | LPL (0.62) | LPLLIPGTHRBCA2MGLL | |
| SCHEMBL97681 | 0.84 | CA2 (0.54) | LPLLIPGTHRBCA2MGLL | |
| SCHEMBL342880 | 0.83 | LPL (0.50) | LPLLIPGTHRBCA2MGLL | |
| SCHEMBL1101345 | 0.82 | ESR1 (0.59) | LPLLIPGTHRBCA2MGLL | |
| SCHEMBL28216919 | 0.82 | TP53 (0.46) | CNR2TAAR1ALDH1A1TP53ADRA2A | |
| SCHEMBL27887291 | 0.82 | CA2 (0.52) | LPLLIPGTHRBCA2MGLL | |
| SCHEMBL9839848 | 0.82 | LPL (0.59) | LPLLIPGTHRBCA2MGLL | |
| SCHEMBL10952838 | 0.82 | GFER (0.47) | CA2L3MBTL1TAAR1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 545 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024118535-A1 | SYNTHESIS AND PURIFICATION OF SUBSTITUTED PYRAZINES | MEDIBEACON INC. (US) | 2024-06-06 | — | — | WO | claimed |
| US-20240182430-A1 | SYNTHESIS OF SUBSTITUTED PYRAZINES | MEDIBEACON INC. | 2024-06-06 | — | — | US | claimed |
| EP-4269391-A1 | SYNTHESIS AND USE OF 1-BENZYL-4-METHYL-5-ALKOXY-1,2,3,6-TETRAHYDROPYRIDINE DERIVATIVE | Zhejiang Ausun Pharmaceutical Co., Ltd. (CN) | 2023-11-01 | — | — | EP | claimed |
| CN-111484438-B | Polysubstituted indole derivative and metal catalysis preparation method thereof | 湖北科技学院 | 2023-02-03 | — | — | CN | claimed |
| CN-112645866-A | Synthesis and application of 1-benzyl-4-methyl-5-alkoxy-1, 2,3, 6-tetrahydropyridine derivative | 浙江奥翔药业股份有限公司 | 2021-04-13 | — | — | CN | claimed |
| CN-111484438-A | Polysubstituted indole derivative and metal catalysis preparation method thereof | 湖北科技学院 | 2020-08-04 | — | — | CN | claimed |
| CN-108530422-A | A kind of preparation method of 2- substitutions -1,3- dithiane derivatives | 兰州大学 | 2018-09-14 | — | — | CN | claimed |
| CN-108191882-A | A kind of preparation method of polyol acetal class compound | 泰山医学院 | 2018-06-22 | — | — | CN | claimed |
| CN-105555754-B | The isomerization method of double (amino methyl) hexamethylenes | 三菱瓦斯化学株式会社 | 2017-10-20 | — | — | CN | claimed |
| US-9745288-B2 | Compounds and methods for treating cancer by inhibiting the urokinase receptor | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2017-08-29 | — | — | US | claimed |
| US-6451937-B1 | BY THERMALLY REACTING A FUNCTIONALIZING REAGENT AND THE HYDROCARBON IN THE PRESENCE OF A TRANSITION METAL COORDINATION CATALYST | SHELL OIL COMPANY | 2002-09-17 | — | — | US | claimed |
| US-20010039349-A1 | Selective, Catalytic, thermal functionalization of secondary or aromatic C-H cyclic hydrocarbon bonds | SHELL OIL COMPANY | 2001-11-08 | — | — | US | claimed |
| EP-1147079-A2 | BETA-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | Bayer Aktiengesellschaft (DE) | 2001-10-24 | — | — | EP | claimed |
| WO-2000041469-A2 | β-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-07-20 | — | — | WO | claimed |
| US-5582942-A | BINDER RESIN COMPRISES A COPOLYMER INCLUDING A (METH)ACRYLIC ACID ESTER CONTAINING AN AROMATIC RING AND A VINYL MONOMER HAVING ONE TO THREE ACID FUNCTIONAL GROUPS | FUJI PHOTO FILM CO., LTD. (JP) | 1996-12-10 | — | — | US | claimed |
| US-5510519-A | OPTICAL RESOLUTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-04-23 | — | — | US | claimed |
| EP-0508307-B1 | Optically active secondary amine compound; process for producing optically active secondary amine compound and process for producing optically active carboxylic acid by using said compound | SUMITOMO CHEMICAL CO (JP) | 1995-11-29 | — | — | EP | claimed |
| US-5298660-A | Compound containing an assymetrical carbon atom | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-03-29 | — | — | US | claimed |
| EP-0508307-A2 | Optically active secondary amine compound; process for producing optically active secondary amine compound and process for producing optically active carboxylic acid by using said compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-10-14 | — | — | EP | claimed |
| US-4593090-A | Containing perhydrofuran or pyran ring structure | GOGO KIMURA (JP) | 1986-06-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240182430-A1 | SYNTHESIS OF SUBSTITUTED PYRAZINES | DHPS, PFAS, NISCH | LPL 4271/4885LIPG 4804/4885THRB 2682/4885 |
| US-20010039349-A1 | Selective, Catalytic, thermal functionalization of secondary or aromatic C-H cyclic hydrocarbon bonds | AHR, PAH, HRH3 | LPL 2118/4885LIPG 2008/4885THRB 1820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.