Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 8/20 | 0.49 |
| ▸ | PARP15 | Q460N3 | 7/20 | 0.49 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 3/20 | 0.44 |
| ▸ | ACACA | Q13085 | 2/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL983929 | 0.84 | PARP10 (0.53) | PARP10PARP15PARP2ACACBACACA | |
| SCHEMBL716744 | 0.81 | MAOB (0.55) | PARP10PARP15PARP2ACACBACACA | |
| SCHEMBL8651126 | 0.80 | PARP10 (0.48) | PARP10PARP15PARP2MTNR1AACACB | |
| SCHEMBL18374257 | 0.79 | PARP10 (0.56) | PARP10PARP15PARP2ACACBACACA | |
| SCHEMBL5085580 | 0.77 | PARP10 (0.60) | PARP10PARP15MAOB | |
| SCHEMBL22389473 | 0.77 | PARP10 (0.49) | PARP10PARP15PARP2MTNR1AACACA | |
| SCHEMBL5730634 | 0.76 | ALDH1A1 (0.62) | HSD17B1MAOB | |
| SCHEMBL1390989 | 0.75 | PARP10 (0.53) | PARP10PARP15PARP2SCN9ANR1H4 | |
| SCHEMBL2087536 | 0.74 | PARP15 (0.70) | PARP10PARP15PARP2ACACBNR1H4 | |
| SCHEMBL13603957 | 0.73 | HSD17B1 (0.44) | HSD17B1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247594-A1 | PYRROLOPYRIMIDINECARBOXAMIDES | Nycomed GmbH (DE) | 2010-11-10 | — | — | EP | disclosed |
| WO-2009106531-A1 | PYRROLOPYRIMIDINECARBOXAMIDES | NYCOMED GMBH (DE) | 2009-09-03 | — | — | WO | disclosed |