Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.60 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.60 |
| ▸ | MAOB | P27338 | 13/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 3/20 | 0.52 |
| ▸ | PPARD | Q03181 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4653952 | 0.87 | PARP10 (0.60) | PARP10PARP15MAOBALDH1A1MAOA | |
| SCHEMBL2964664 | 0.86 | PARP10 (0.60) | PARP10PARP15MAOBALDH1A1MAPK1 | |
| SCHEMBL716744 | 0.81 | MAOB (0.55) | PARP10PARP15MAOBMAOA | |
| SCHEMBL2206445 | 0.80 | PARP10 (0.51) | PARP10PARP15MAOBMAOA | |
| SCHEMBL8903105 | 0.79 | CA12 (0.55) | PARP10PARP15ALDH1A1CYP3A4HPGD | |
| SCHEMBL11068644 | 0.79 | MAOB (0.56) | MAOBALDH1A1CYP3A4HPGDMAPK1 | |
| SCHEMBL983929 | 0.78 | PARP10 (0.53) | PARP10PARP15 | |
| SCHEMBL25210537 | 0.78 | NFKB1 (0.60) | MAOBALDH1A1CYP3A4HPGDMAPK1 | |
| SCHEMBL6958286 | 0.78 | PARP10 (0.72) | PARP10PARP15ALDH1A1 | |
| SCHEMBL3428815 | 0.77 | PARP10 (0.49) | PARP10PARP15MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008018692-A1 | NOVEL CHALCONE DERIVATIVES WHICH INHIBIT THE IL-5 ACTIVITY | THE INDUSTRY AND ACADEMIC COOPERATION IN CHUNGNAM NATIONAL UNIVERSITY (IAC) (KR) | 2008-02-14 | — | — | WO | disclosed |