SCHEMBL3428867

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3430571	0.81	ELANE (0.47)	PTGER4NPC1RAB9AELANEALDH1A1
	SCHEMBL3431593	0.79	NPC1 (0.49)	NPC1RAB9AELANETP53HTT
	SCHEMBL3432880	0.78	KMT2A (0.51)	NPC1RAB9AELANEHTTALDH1A1
	SCHEMBL30695085	0.76	PTGER4 (0.58)	PTGER4NPC1RAB9AEGFRSRC
	SCHEMBL17038814	0.76	PTGER4 (0.58)	PTGER4NPC1RAB9AEGFRSRC
	SCHEMBL3432576	0.76	ELANE (0.54)	PTGER4NPC1RAB9AELANETP53
	SCHEMBL3427977	0.75	KCNA5 (0.54)	NPC1RAB9ATP53ALDH1A1HPGD
	SCHEMBL14584142	0.73	RORC (0.49)	PTGER4NPC1RAB9AEGFRSRC
	SCHEMBL3431965	0.72	NPC1 (0.50)	NPC1RAB9AELANEALDH1A1KDM4E
	SCHEMBL13671628	0.71	SCN9A (0.53)	NPC1RAB9AELANEALDH1A1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.