SCHEMBL3430571

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3431965	0.92	NPC1 (0.50)	ELANECNR1BRD4ROCK1NPC1
	SCHEMBL3431593	0.83	NPC1 (0.49)	ELANENPC1RAB9ASMN1; SMN2MEN1
	SCHEMBL3432576	0.82	ELANE (0.54)	ELANEPTGER4ROCK1NPC1RAB9A
	SCHEMBL3428867	0.81	PTGER4 (0.46)	ELANECNR1PTGER4NPC1RAB9A
	SCHEMBL3432880	0.80	KMT2A (0.51)	ELANENPC1RAB9ASMN1; SMN2MEN1
	SCHEMBL3431330	0.78	ELANE (0.53)	ELANECNR1PTGER4ROCK1NPC1
	SCHEMBL3755136	0.75	RAB9A (0.54)	ROCK1NPC1RAB9ASMN1; SMN2MEN1
	SCHEMBL3428243	0.74	PTGER4 (0.52)	ELANECNR1PTGER4ROCK1NPC1
	SCHEMBL13051117	0.73	TRPV1 (0.44)	CNR1ROCK1PKM
	SCHEMBL3428314	0.72	TSHR (0.55)	ELANENPC1RAB9ASMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.