SCHEMBL342900

SCHEMBL342900

O=C(Cl)CC1SCCCS1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3047626 0.78 FAAH (0.37) FAAH
SCHEMBL343431 0.77 TSHR (0.32) FAAH
SCHEMBL15061657 0.76 FAAH (0.32) FAAH
SCHEMBL9156177 0.70 FAAH (0.33) FAAH
SCHEMBL800964 0.67
SCHEMBL1194885 0.66
SCHEMBL5314758 0.65 FOLH1 (0.43) FAAH
SCHEMBL15061640 0.65
SCHEMBL9670422 0.64
SCHEMBL9306669 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE46234-E1 Tissue adhesive and sealant comprising polyglycerol aldehyde ACTAMAX SURGICAL MATERIALS, LLC (US) 2016-12-13 US disclosed
EP-2411062-B1 TISSUE ADHESIVE AND SEALANT COMPRISING POLYGLYCEROL ALDEHYDE ACTAMAX SURGICAL MATERIALS LLC (US) 2014-08-20 EP disclosed
US-8680200-B2 Polyglycerol aldehydes ACTAMAX SURGICAL MATERIALS LLC (US) 2014-03-25 US disclosed
US-8404779-B2 Tissue adhesive and sealant comprising polyglycerol aldehyde ACTAMAX SURGICAL MATERIALS LLC (US) 2013-03-26 US disclosed
EP-2411448-B1 POLYGLYCEROL ALDEHYDES ACTAMAX SURGICAL MATERIALS LLC (US) 2013-03-20 EP disclosed
US-20120029149-A1 POLYGLYCEROL ALDEHYDES ACTAMAX SURGICAL MATERIALS, LLC (US) 2012-02-02 US disclosed
EP-2411448-A1 POLYGLYCEROL ALDEHYDES Actamax Surgical Materials LLC (US) 2012-02-01 EP disclosed
EP-2411062-A1 TISSUE ADHESIVE AND SEALANT COMPRISING POLYGLYCEROL ALDEHYDE Actamax Surgical Materials LLC (US) 2012-02-01 EP disclosed
US-20120014909-A1 TISSUE ADHESIVE AND SEALANT COMPRISING POLYGLYCEROL ALDEHYDE ACTAMAX SURGICAL MATERIALS, LLC (US) 2012-01-19 US disclosed
WO-2010111570-A1 POLYGLYCEROL ALDEHYDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-09-30 WO disclosed
WO-2010111594-A1 TISSUE ADHESIVE AND SEALANT COMPRISING POLYGLYCEROL ALDEHYDE E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-09-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120029149-A1 POLYGLYCEROL ALDEHYDES GGH, TGM3, FABP2 FAAH 153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.