Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5314758 | 0.80 | FOLH1 (0.43) | TSHRFAAHALDH1A1 | |
| SCHEMBL342900 | 0.77 | FAAH (0.32) | FAAH | |
| SCHEMBL9670422 | 0.72 | — | — | |
| SCHEMBL15757375 | 0.71 | LMNA (0.49) | TSHRALDH1A1 | |
| SCHEMBL8531514 | 0.70 | FOLH1 (0.41) | TSHRALDH1A1 | |
| SCHEMBL9073046 | 0.65 | CHRM2 (0.35) | TSHR | |
| SCHEMBL4189336 | 0.65 | — | — | |
| SCHEMBL3047626 | 0.65 | FAAH (0.37) | TSHRFAAH | |
| SCHEMBL7939245 | 0.65 | — | — | |
| SCHEMBL279341 | 0.65 | HPGD (0.50) | ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE46234-E1 | Tissue adhesive and sealant comprising polyglycerol aldehyde | ACTAMAX SURGICAL MATERIALS, LLC (US) | 2016-12-13 | — | — | US | disclosed |
| EP-2411062-B1 | TISSUE ADHESIVE AND SEALANT COMPRISING POLYGLYCEROL ALDEHYDE | ACTAMAX SURGICAL MATERIALS LLC (US) | 2014-08-20 | — | — | EP | disclosed |
| US-8680200-B2 | Polyglycerol aldehydes | ACTAMAX SURGICAL MATERIALS LLC (US) | 2014-03-25 | — | — | US | disclosed |
| US-8404779-B2 | Tissue adhesive and sealant comprising polyglycerol aldehyde | ACTAMAX SURGICAL MATERIALS LLC (US) | 2013-03-26 | — | — | US | disclosed |
| EP-2411448-B1 | POLYGLYCEROL ALDEHYDES | ACTAMAX SURGICAL MATERIALS LLC (US) | 2013-03-20 | — | — | EP | disclosed |
| US-20120029149-A1 | POLYGLYCEROL ALDEHYDES | ACTAMAX SURGICAL MATERIALS, LLC (US) | 2012-02-02 | — | — | US | disclosed |
| EP-2411448-A1 | POLYGLYCEROL ALDEHYDES | Actamax Surgical Materials LLC (US) | 2012-02-01 | — | — | EP | disclosed |
| EP-2411062-A1 | TISSUE ADHESIVE AND SEALANT COMPRISING POLYGLYCEROL ALDEHYDE | Actamax Surgical Materials LLC (US) | 2012-02-01 | — | — | EP | disclosed |
| US-20120014909-A1 | TISSUE ADHESIVE AND SEALANT COMPRISING POLYGLYCEROL ALDEHYDE | ACTAMAX SURGICAL MATERIALS, LLC (US) | 2012-01-19 | — | — | US | disclosed |
| WO-2010111570-A1 | POLYGLYCEROL ALDEHYDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-09-30 | — | — | WO | disclosed |
| WO-2010111594-A1 | TISSUE ADHESIVE AND SEALANT COMPRISING POLYGLYCEROL ALDEHYDE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-09-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120029149-A1 | POLYGLYCEROL ALDEHYDES | GGH, TGM3, FABP2 | TSHR 4315/4885FAAH 153/4885ALDH1A1 75/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.