Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 3/20 | 0.45 |
| ▸ | SLC16A1 | P53985 | 3/20 | 0.45 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 6/20 | 0.44 |
| ▸ | FABP3 | P05413 | 2/20 | 0.43 |
| ▸ | FABP4 | P15090 | 2/20 | 0.43 |
| ▸ | MGLL | Q99685 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CCKAR | P32238 | 1/20 | 0.41 |
| ▸ | SLC5A1 | P13866 | 3/20 | 0.40 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3431644 | 0.94 | SLC16A3 (0.46) | SLC16A3SLC16A1MCTS1FAAHFABP3 | |
| SCHEMBL3430158 | 0.92 | SLC16A3 (0.43) | SLC16A3SLC16A1MCTS1FAAHFABP3 | |
| SCHEMBL3431968 | 0.89 | AVPR1B (0.48) | — | |
| SCHEMBL3426584 | 0.89 | SLC16A3 (0.57) | SLC16A3SLC16A1MCTS1FAAHMGLL | |
| SCHEMBL3429446 | 0.87 | SLC16A3 (0.48) | SLC16A3SLC16A1MCTS1FAAHFABP3 | |
| SCHEMBL1110679 | 0.87 | SLC5A1 (0.51) | SLC16A3SLC16A1MCTS1FAAHMGLL | |
| SCHEMBL1110698 | 0.85 | PPP1CA (0.50) | SLC16A3SLC16A1MCTS1FAAHFABP3 | |
| SCHEMBL1765033 | 0.85 | FAAH (0.58) | SLC16A3SLC16A1MCTS1FAAHMGLL | |
| SCHEMBL3430227 | 0.84 | ALDH1A1 (0.45) | SLC16A3SLC16A1MCTS1FAAHFABP3 | |
| SCHEMBL3431941 | 0.82 | ALDH1A1 (0.45) | SLC16A3SLC16A1MCTS1FABP3FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2254885-A1 | (PYRAZOLYL CARBONYL)IMIDAZOLIDINONE DERIVATIVES FOR THE TREATMENT OF RETROVIRAL DISEASES | AiCuris GmbH & Co. KG (DE) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009115213-A1 | (PYRAZOLYL CARBONYL)IMIDAZOLIDINONE DERIVATIVES FOR THE TREATMENT OF RETROVIRAL DISEASES | AICURIS GMBH & CO. KG (DE) | 2009-09-24 | — | — | WO | disclosed |