Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 14/20 | 0.62 |
| ▸ | TRPV3 | Q8NET8 | 5/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3407765 | 0.88 | FAAH (0.66) | FAAHCYP2D6 | |
| SCHEMBL12538857 | 0.82 | TRPV3 (0.67) | FAAHTRPV3 | |
| SCHEMBL3408600 | 0.81 | FAAH (0.62) | FAAHTRPV3 | |
| SCHEMBL13663433 | 0.81 | FAAH (0.62) | FAAHTRPV3 | |
| SCHEMBL14292066 | 0.80 | AURKA (0.55) | FAAHCYP2D6 | |
| SCHEMBL4779880 | 0.78 | FAAH (0.49) | FAAHCYP2D6 | |
| Trifluoroacetic Acid SCHEMBL4303325 | 0.77 | FAAH (0.57) | FAAHTRPV3 | |
| SCHEMBL4298846 | 0.77 | FAAH (1.00) | FAAH | |
| SCHEMBL4303442 | 0.77 | FAAH (1.00) | FAAH | |
| SCHEMBL3409393 | 0.76 | FAAH (0.49) | FAAHCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2254415-A1 | ARYL-HYDROXYETHYLAMINO-PYRIMIDINES AND TRIAZINES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE | Janssen Pharmaceutica, N.V. (BE) | 2010-12-01 | — | — | EP | claimed |
| WO-2009105220-A1 | ARYL-HYDROXYETHYLAMINO-PYRIMIDINES AND TRIAZINES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-08-27 | — | — | WO | claimed |