Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 17/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4727781 | 0.85 | FAAH (0.56) | FAAH | |
| SCHEMBL4729308 | 0.83 | FAAH (0.46) | FAAHCYP2D6 | |
| SCHEMBL14292081 | 0.82 | CYP2D6 (0.61) | FAAHCYP2D6 | |
| SCHEMBL4847869 | 0.82 | CYP2D6 (0.61) | FAAHCYP2D6 | |
| SCHEMBL4726854 | 0.82 | CYP2D6 (0.61) | FAAHCYP2D6 | |
| SCHEMBL14292652 | 0.82 | STK17A (0.50) | FAAH | |
| SCHEMBL14292795 | 0.80 | AURKA (0.52) | FAAH | |
| SCHEMBL14292066 | 0.79 | AURKA (0.55) | FAAHCYP2D6 | |
| SCHEMBL14292650 | 0.79 | AURKA (0.52) | FAAH | |
| SCHEMBL3429809 | 0.78 | FAAH (0.62) | FAAHCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008024634-A1 | PYRIMDINE COMPOUNDS USEFUL AS KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-02-28 | — | — | WO | disclosed |