Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1461768 | 0.80 | MAOA (0.44) | ATMMAOAMAOBCYP2C9HDAC3 | |
| SCHEMBL1979794 | 0.79 | MAOA (0.62) | ATMMAOAMAOBCYP2C9HDAC3 | |
| SCHEMBL3236129 | 0.78 | MAOA (0.58) | ATMMAOAMAOBCYP2C9HDAC3 | |
| SCHEMBL11781441 | 0.77 | CYP2C9 (0.44) | ATMMAOAMAOBCYP2C9HDAC3 | |
| SCHEMBL8655488 | 0.76 | MAOA (0.40) | ATMMAOAMAOBCYP2C9HDAC3 | |
| SCHEMBL5544515 | 0.69 | MAOA (0.46) | ATMMAOAMAOBCYP2C9HDAC3 | |
| SCHEMBL22851772 | 0.66 | AHR (0.42) | ATMMAOAMAOBCYP2C9HDAC3 | |
| SCHEMBL29413779 | 0.65 | MAOA (0.58) | ATMMAOAMAOBCYP2C9HDAC3 | |
| SCHEMBL88261 | 0.65 | MAOA (0.58) | ATMMAOAMAOBCYP2C9HDAC3 | |
| SCHEMBL19458502 | 0.64 | MAOA (0.64) | ATMMAOAMAOBCYP2C9HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7759302-B2 | Octapeptides: Arg-X-Asp-Leu-Asp-Ser-Leu-Arg where X is a 2-aminoaulfonylaminoalkanoic acid and optionally having various end groups; biologically active as ligands of blood platelet integrin GPIIbIIIa and the alpha v integrins | MERCK PATENT GMBH (DE) | 2010-07-20 | — | — | US | disclosed |
| US-20060148716-A1 | Peptidic sulfonamides | MERCK PATENT GMBH (DE) | 2006-07-06 | — | — | US | disclosed |
| CN-1361792-A | Cyclic peptide derivatives as inhibitors of integrin alpha/beta | MERCK PATENT GMBH (DE) | 2002-07-31 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060148716-A1 | Peptidic sulfonamides | ITGB3, ITGA2B, ITGA2 | ATM 2944/4885MAOA 4620/4885MAOB 4494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.