Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.36 |
| ▸ | DRD3 | P35462 | 6/20 | 0.33 |
| ▸ | DRD1 | P21728 | 4/20 | 0.33 |
| ▸ | DRD4 | P21917 | 4/20 | 0.33 |
| ▸ | DRD5 | P21918 | 4/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2121244 | 0.84 | ESR1 (0.40) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL3430803 | 0.83 | MEN1 (0.38) | DRD2MTNR1BNQO2MTNR1ASMN1; SMN2 | |
| SCHEMBL2123807 | 0.79 | DRD2 (0.37) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL2124391 | 0.77 | DRD2 (0.48) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL2122587 | 0.77 | ESR1 (0.38) | DRD2DRD1ESR1ESR2SMN1; SMN2 | |
| SCHEMBL18759887 | 0.76 | SMN1; SMN2 (0.40) | MTNR1BSMN1; SMN2LMNA | |
| SCHEMBL2123572 | 0.76 | ESR2 (0.46) | ESR2 | |
| SCHEMBL2121610 | 0.73 | USP30 (0.34) | LMNA | |
| SCHEMBL25343893 | 0.73 | ESR2 (0.52) | DRD2ESR1ESR2 | |
| SCHEMBL29784593 | 0.73 | ESR2 (0.52) | DRD2ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010146105-A1 | S1P1 AGONISTS COMPRISING A BICYCLIC N-CONTAINING RING | GLAXO GROUP LIMITED (GB) | 2010-12-23 | — | — | WO | disclosed |