Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 5/20 | 0.35 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1365004 | 1.00 | L3MBTL1 (0.36) | L3MBTL1CTSLCTSSCTSBCTSK | |
| SCHEMBL1365748 | 1.00 | L3MBTL1 (0.36) | L3MBTL1CTSLCTSSCTSBCTSK | |
| SCHEMBL1363199 | 0.93 | MAOA (0.39) | L3MBTL1NPC1RAB9A | |
| SCHEMBL1365002 | 0.86 | CXCR1 (0.38) | L3MBTL1CTSLCTSSCTSBCTSK | |
| SCHEMBL12140344 | 0.86 | CXCR1 (0.38) | L3MBTL1CTSLCTSSCTSBCTSK | |
| SCHEMBL12140312 | 0.86 | CXCR1 (0.38) | L3MBTL1CTSLCTSSCTSBCTSK | |
| SCHEMBL12306450 | 0.86 | L3MBTL1 (0.35) | L3MBTL1CTSLCTSSCTSBCTSK | |
| SCHEMBL1363809 | 0.86 | RAB9A (0.34) | L3MBTL1CTSLCTSSCTSBCTSK | |
| SCHEMBL1364446 | 0.86 | RAB9A (0.34) | L3MBTL1CTSLCTSSCTSBCTSK | |
| SCHEMBL1365319 | 0.84 | AR (0.43) | L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2260028-A2 | SELECTIVE ANDROGEN RECEPTOR MODULATORS | Radius Health, Inc. (US) | 2010-12-15 | — | — | EP | disclosed |
| WO-2009105214-A2 | SELECTIVE ANDROGEN RECEPTOR MODULATORS | RADIUS HEALTH, INC. (US) | 2009-08-27 | — | — | WO | disclosed |