SCHEMBL3430813

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3433127	0.89	HTT (0.47)	MAPTKDM4EMEN1KMT2AALDH1A1
	SCHEMBL3431653	0.80	NPC1 (0.52)	MAPTKDM4EMEN1KMT2AALDH1A1
	SCHEMBL4250971	0.78	CNR1 (0.46)	MAPTKDM4EMEN1KMT2AALDH1A1
	SCHEMBL3430598	0.76	LRRK2 (0.53)	KDM4ERAB9ASMN1; SMN2TSHRAKR1B1
	SCHEMBL3428566	0.76	SMN1; SMN2 (0.49)	MAPTKDM4EMEN1KMT2AALDH1A1
	SCHEMBL3431088	0.75	KDM4E (0.45)	MAPTKDM4EMEN1KMT2AALDH1A1
	SCHEMBL6532344	0.74	ALDH1A1 (0.48)	MAPTALDH1A1HTTLMNARAB9A
	SCHEMBL3428278	0.72	NPC1 (0.55)	MAPTKDM4EMEN1KMT2AALDH1A1
	SCHEMBL3429672	0.72	ATR (0.50)	MAPTKDM4EMEN1KMT2AALDH1A1
	SCHEMBL4250973	0.72	PHOSPHO1 (0.45)	MAPTMEN1KMT2AALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.