SCHEMBL3430944

SCHEMBL3430944

CCOc1c(Cl)cccc1C=Cc1nc(C(Cl)(Cl)Cl)nc(C(Cl)(Cl)Cl)n1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.35
NPC1 O15118 5/20 0.34
MEN1 O00255 4/20 0.34
KMT2A Q03164 4/20 0.34
AGTR1 P30556 1/20 0.34
ATM Q13315 1/20 0.34
HRH4 Q9H3N8 1/20 0.34
RAB9A P51151 4/20 0.33
ALDH1A1 P00352 2/20 0.33
MAPT P10636 1/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
KDM4E B2RXH2 3/20 0.32
CASP3 P42574 1/20 0.32
SENP7 Q9BQF6 1/20 0.32
SENP6 Q9GZR1 1/20 0.32
POLB P06746 1/20 0.31
GAA P10253 1/20 0.31
TSHR P16473 1/20 0.31
ELANE P08246 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8570243 0.81 KMT2A (0.45) L3MBTL1NPC1MEN1KMT2AAGTR1
SCHEMBL8570242 0.81 KMT2A (0.45) L3MBTL1NPC1MEN1KMT2AAGTR1
SCHEMBL8626189 0.73 KMT2A (0.40) L3MBTL1NPC1MEN1KMT2AATM
SCHEMBL1629064 0.72 RELA (0.53) NPC1MEN1KMT2AATMRAB9A
SCHEMBL1629063 0.72 RELA (0.53) NPC1MEN1KMT2AATMRAB9A
SCHEMBL9627254 0.72 KMT2A (0.42) NPC1MEN1KMT2AATMRAB9A
SCHEMBL6705480 0.71 HRH4 (0.46) NPC1MEN1KMT2AHRH4RAB9A
SCHEMBL6705475 0.71 HRH4 (0.46) NPC1MEN1KMT2AHRH4RAB9A
SCHEMBL147046 0.71 NFE2L2 (0.50) NPC1MEN1KMT2ARAB9AALDH1A1
SCHEMBL147047 0.71 NFE2L2 (0.50) NPC1MEN1KMT2ARAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7648738-B2 for photopolymerization; photography, relief imaging; color filters CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-01-19 US disclosed
US-20060241259-A1 Oxime ester photoinitiators with heteroaromatic groups CIBA CORPORATION 2006-10-26 US disclosed