Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7065964 | 0.89 | CNR1 (0.41) | SOAT1MEN1FAAHTP53CYP1A2 | |
| SCHEMBL7699295 | 0.85 | FAAH (0.50) | SOAT1MEN1FAAHTP53CYP1A2 | |
| SCHEMBL7695119 | 0.85 | FAAH (0.50) | SOAT1MEN1FAAHTP53CYP1A2 | |
| SCHEMBL7698631 | 0.85 | FAAH (0.50) | SOAT1MEN1FAAHTP53CYP1A2 | |
| SCHEMBL498067 | 0.73 | — | — | |
| SCHEMBL6424415 | 0.73 | — | — | |
| SCHEMBL1259870 | 0.72 | — | — | |
| SCHEMBL7974672 | 0.71 | LMNA (0.37) | SOAT1MEN1FAAHTP53CYP1A2 | |
| SCHEMBL10771318 | 0.71 | PAOX (0.38) | MEN1CYP1A2CYP3A4KMT2ALMNA | |
| SCHEMBL6418788 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8637550-B2 | Heteroaryl diamide compounds useful as MMP-13 inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-01-28 | — | — | US | disclosed |
| WO-2010056585-A2 | HETEROARYL DIAMIDE COMPOUNDS USEFUL AS MMP-13 INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-05-20 | — | — | WO | disclosed |