SCHEMBL3431981

SCHEMBL3431981

CN1CC1=O.COC(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 4/20 0.45
CYP1A2 P05177 1/20 0.38
HIF1A Q16665 1/20 0.38
LMNA P02545 1/20 0.35
CHRM2 P08172 1/20 0.35
CHRM4 P08173 1/20 0.35
CHRM5 P08912 1/20 0.35
THRB P10828 1/20 0.35
CHRM1 P11229 1/20 0.35
CHRM3 P20309 1/20 0.35
BLM P54132 1/20 0.34
MCOLN3 Q8TDD5 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
CRBN Q96SW2 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
BRD2 P25440 1/20 0.33
PIK3CD O00329 1/20 0.33
ALDH1A1 P00352 3/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methoxymethane SCHEMBL28761895 0.80
SCHEMBL12748060 0.76
SCHEMBL1681009 0.76
SCHEMBL28813952 0.75 KMT2A (0.35) BRD4CYP1A2HIF1ALMNAMEN1
SCHEMBL10692571 0.74 TSHR (0.52) SMN1; SMN2ALDH1A1MAPTTSHR
SCHEMBL37752 0.72
SCHEMBL27553773 0.72 ALDH1A1 (0.54) SMN1; SMN2ALDH1A1TSHR
SCHEMBL12049989 0.72 P2RX7 (0.44) BRD4KMT2ASMN1; SMN2BRD2PIK3CD
Cyclopropane SCHEMBL18825318 0.70
Cyclohexane SCHEMBL11243795 0.70 ALDH1A1 (0.44) LMNAMEN1KMT2ASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2482972-A2 A PROCESS AND CATALYSTS FOR PRODUCING ALKYLENE AND/OR DIALKYL CARBONATES Majer Laboratory, S.r.o (CZ) 2012-08-08 EP disclosed
EP-1265842-B1 PROCESS FOR CO-PRODUCTION OF DIALKYL CARBONATE AND ALKANEDIOL BADGER LICENSING LLC (US) 2010-10-13 EP disclosed
WO-2009143785-A2 A PROCESS AND CATALYSTS FOR PRODUCING ALKYLENE AND/OR DIALKYL CARBONATES MAJER LABORATORY, S.R.O (CZ) 2009-12-03 WO disclosed
CN-100395019-C Catalyst used for synthesizing dimethyl carbonate from ured and methanol and its preparation method and application SHANXI COAL CHEM INST (CN) 2008-06-18 CN disclosed
EP-1740529-A4 PROCESS FOR MAKING DIALKYL CARBONATES CATALYTIC DISTILLATION TECH (US) 2008-02-20 EP disclosed
US-7314947-B2 Process for making dialkyl carbonates CATALYTIC DISTILLATION TECHNOLOGIES (US) 2008-01-01 US disclosed
US-7279592-B2 Process for making dialkyl carbonates CATALYTIC DISTILLATION TECHNOLOGIES (US) 2007-10-09 US disclosed
EP-1740529-A2 PROCESS FOR MAKING DIALKYL CARBONATES Catalytic Distillation Technologies (US) 2007-01-10 EP disclosed
US-7074951-B2 Process for making dialkyl carbonates CATALYTIC DISTILLATION TECHNOLOGIES 2006-07-11 US disclosed
US-20060142606-A1 Process for making dialkyl carbonates CATALYTIC DISTILLATION TECHNOLOGIES 2006-06-29 US disclosed
US-6342623-B1 REACTING ALKYLENE CARBONATE WITH ALKANOL IN PRESENCE OF AMORPHOUS ALUMINOSILICATE CATALYST COMPRISING ALKALI METAL AND/OR ALKALINE EARTH METAL EXXONMOBIL CHEMICAL PATENTS INC. 2002-01-29 US disclosed
US-RE37337-E1 DIMETHYL CARBONATE; REACTION OF PRIMARY ALCOHOL, SUCH AS METHANOL, WITH UREA IN PRESENCE OF NOVEL ORGANOTIN CATALYST COMPLEX WITH HIGH BOILING ELECTRON DONOR COMPOUND ACTING AS SOLVENT; CONCURRENT DISTILLATION CATALYTIC DISTILLATION TECHNOLOGIES 2001-08-21 US disclosed
WO-2001056971-A1 PROCESS FOR CO-PRODUCTION OF DIALKYL CARBONATE AND ALKANEDIOL MOBIL OIL CORPORATION (US) 2001-08-09 WO disclosed
WO-2001044158-A1 PROCESS FOR CO-PRODUCTION OF DIALKYL CARBONATE AND ALKANEDIOL MOBIL OIL CORPORATION (US) 2001-06-21 WO disclosed
US-6207850-B1 TRANSESTERIFICATION OF ALKYLENE CARBONATE WITH AN ALCOHOL MOBIL OIL CORPORATION 2001-03-27 US disclosed
US-6166240-A Process for co-production of dialkyl carbonate and alkanediol MOBIL OIL CORPORATION (US) 2000-12-26 US disclosed
US-6162940-A Process for co-production of dialkyl carbonate and alkanediol MOBIL OIL CORPORATION (US) 2000-12-19 US disclosed
WO-2000073256-A1 PROCESS FOR CO-PRODUCTION OF DIALKYL CARBONATE AND ALKANEDIOL MOBIL OIL CORPORATION (US) 2000-12-07 WO disclosed
US-6010976-A Catalyst for making dialkyl carbonates CATALYTIC DISTILLATION TECHNOLOGIES (US) 2000-01-04 US disclosed
US-5902894-A REACTING UREA AND A PRIMARY ALCOHOL IN A REACTION ZONE WITH AN ORGANOTIN COMPOUND AND A HIGH BOILING ELECTRON DONOR ATOM CONTAINING SOLVENT CATALYTIC DISTILLATION TECHNOLOGIES (US) 1999-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060142606-A1 Process for making dialkyl carbonates ADH1C, CPS1, C1S BRD4 4074/4885CYP1A2 548/4885HIF1A 1918/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.