Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3433243 | 0.78 | CHRM2 (0.44) | TP53ALDH1A1KCNQ2KDM4EUSP2 | |
| SCHEMBL3432341 | 0.74 | TP53 (0.34) | TP53ALDH1A1KDM4EUSP2TSHR | |
| SCHEMBL2201933 | 0.73 | SMN1; SMN2 (0.53) | TP53ALDH1A1USP2TSHRSMN1; SMN2 | |
| SCHEMBL7038721 | 0.71 | ALDH1A1 (0.61) | TP53ALDH1A1KCNQ2KDM4ESMN1; SMN2 | |
| SCHEMBL17067809 | 0.71 | ALDH1A1 (0.53) | TP53ALDH1A1KCNQ2KDM4ETSHR | |
| SCHEMBL25567784 | 0.70 | TP53 (0.51) | TP53ALDH1A1KDM4E | |
| SCHEMBL28455024 | 0.70 | TP53 (0.53) | TP53ALDH1A1KCNQ2KDM4EMEN1 | |
| SCHEMBL21391490 | 0.69 | SRD5A1 (0.54) | TP53ALDH1A1KCNQ2KDM4EMEN1 | |
| SCHEMBL2201637 | 0.68 | ALDH1A1 (0.46) | TP53ALDH1A1KCNQ2KDM4ETSHR | |
| SCHEMBL2201633 | 0.68 | ALDH1A1 (0.46) | TP53ALDH1A1KCNQ2KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163910-B2 | Amide-substituted xanthene dyes | ELITECH HOLDING B.V. (NL) | 2012-04-24 | — | — | US | disclosed |
| US-20090093612-A1 | AMIDE-SUBSTITUTED XANTHENE DYES | EPOCH BIOSCIENCES, INC. (US) | 2009-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090093612-A1 | AMIDE-SUBSTITUTED XANTHENE DYES | ANXA5, PHOSPHO1, TPST2 | TP53 2340/4885ALDH1A1 4277/4885KCNQ2 3898/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.