Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 6/20 | 0.42 |
| ▸ | DRD5 | P21918 | 6/20 | 0.42 |
| ▸ | DRD2 | P14416 | 5/20 | 0.42 |
| ▸ | DRD3 | P35462 | 5/20 | 0.42 |
| ▸ | DRD4 | P21917 | 4/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3431666 | 0.91 | DRD2 (0.44) | CHRM2CHRM4ALDH1A1PDK1PDK2 | |
| SCHEMBL28109941 | 0.91 | CHRM2 (0.48) | CHRM2CHRM4ALDH1A1PDK1PDK2 | |
| SCHEMBL2096904 | 0.84 | DRD1 (0.48) | CHRM2CHRM4DRD1DRD5DRD2 | |
| SCHEMBL3433207 | 0.78 | TP53 (0.43) | CHRM2CHRM4ALDH1A1USP2TSHR | |
| SCHEMBL2201933 | 0.78 | SMN1; SMN2 (0.53) | ALDH1A1USP2TSHRSMN1; SMN2TP53 | |
| SCHEMBL2097897 | 0.74 | ESR2 (0.46) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL11601096 | 0.74 | SMN1; SMN2 (0.49) | CHRM2CHRM4ALDH1A1DRD1DRD5 | |
| SCHEMBL1282891 | 0.74 | DRD1 (0.53) | CHRM2CHRM4ALDH1A1PDK1PDK2 | |
| SCHEMBL17602223 | 0.72 | DRD1 (0.48) | PDK1PDK2PDK3PDK4DRD1 | |
| SCHEMBL6575713 | 0.72 | KMT2A (0.46) | ALDH1A1SMN1; SMN2ESR1ESR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163910-B2 | Amide-substituted xanthene dyes | ELITECH HOLDING B.V. (NL) | 2012-04-24 | — | — | US | disclosed |
| US-7767834-B2 | Phosphonylated fluorescent dyes and conjugates | ELITECH HOLDING B.V. (NL) | 2010-08-03 | — | — | US | disclosed |
| US-20090093612-A1 | AMIDE-SUBSTITUTED XANTHENE DYES | EPOCH BIOSCIENCES, INC. (US) | 2009-04-09 | — | — | US | disclosed |
| US-20080207887-A1 | PHOSPHONYLATED FLUORESCENT DYES AND CONJUGATES | EPOCH BIOSCIENCES, INC. (US) | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207887-A1 | PHOSPHONYLATED FLUORESCENT DYES AND CONJUGATES | PHOSPHO1, PFAS, PHPT1 | CHRM2 4806/4885CHRM4 4449/4885ALDH1A1 1457/4885 |
| US-20090093612-A1 | AMIDE-SUBSTITUTED XANTHENE DYES | ANXA5, PHOSPHO1, TPST2 | CHRM2 3604/4885CHRM4 2438/4885ALDH1A1 4277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.