Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | HTR1B | P28222 | 6/20 | 0.54 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HTR1D | P28221 | 2/20 | 0.50 |
| ▸ | OGG1 | O15527 | 1/20 | 0.50 |
| ▸ | BCL2 | P10415 | 3/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.49 |
| ▸ | BAD | Q92934 | 2/20 | 0.49 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19849754 | 0.94 | MRGPRX4 (0.54) | ALDH1A1KDM4EHPGDTDP1HTR1B | |
| SCHEMBL19844156 | 0.93 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDTDP1HTR1B | |
| SCHEMBL10597687 | 0.85 | KDM4E (0.63) | ALDH1A1KDM4EHPGDTDP1HTR1B | |
| SCHEMBL10391163 | 0.83 | KDM4E (0.57) | ALDH1A1KDM4EHPGDTDP1HTR1B | |
| SCHEMBL1902160 | 0.83 | KDM4E (0.64) | ALDH1A1KDM4EHPGDTDP1HTR1B | |
| SCHEMBL10534409 | 0.83 | KDM4E (0.57) | ALDH1A1KDM4EHPGDTDP1HTR1B | |
| SCHEMBL5289923 | 0.81 | HTR1B (0.77) | ALDH1A1KDM4EHPGDTDP1HTR1B | |
| SCHEMBL27890561 | 0.81 | ALOX5 (0.51) | ALDH1A1KDM4EHPGDTDP1HTR1B | |
| SCHEMBL5144042 | 0.80 | KDM4E (0.54) | ALDH1A1KDM4EHPGDTDP1HTR1B | |
| SCHEMBL28354466 | 0.80 | KDM4E (0.57) | ALDH1A1KDM4EHPGDTDP1HTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9957223-B2 | Bis(aryloxyalkyl) esters of aromatic polycarboxylic acids and method of preparation | ETHOX CHEMICALS LLC (US) | 2018-05-01 | — | — | US | disclosed |
| US-9957223-B2 | Bis(aryloxyalkyl) esters of aromatic polycarboxylic acids and method of preparation | ETHOX CHEMICALS LLC (US) | 2018-05-01 | — | — | US | disclosed |
| US-20180037535-A1 | NOVEL BIS(ARYLOXYALKYL) ESTERS OF AROMATIC POLYCARBOXYLIC ACIDS AND METHOD OF PREPARATION | FIRST NATIONAL BANK OF PENNSYLVANIA | 2018-02-08 | — | — | US | disclosed |
| US-20180037535-A1 | NOVEL BIS(ARYLOXYALKYL) ESTERS OF AROMATIC POLYCARBOXYLIC ACIDS AND METHOD OF PREPARATION | FIRST NATIONAL BANK OF PENNSYLVANIA | 2018-02-08 | — | — | US | disclosed |
| US-9409852-B2 | Bis(aryloxyalkyl) esters of aromatic polycarboxylic acids and method of preparation | ETHOX CHEMICALS, LLC (US) | 2016-08-09 | — | — | US | disclosed |
| US-9409852-B2 | Bis(aryloxyalkyl) esters of aromatic polycarboxylic acids and method of preparation | ETHOX CHEMICALS, LLC (US) | 2016-08-09 | — | — | US | disclosed |
| US-20140031578-A1 | NOVEL BIS(ARYLOXYALKYL) ESTERS OF AROMATIC POLYCARBOXYLIC ACIDS AND METHOD OF PREPARATION | ETHOX CHEMICALS, LLC | 2014-01-30 | — | — | US | disclosed |
| US-20140031578-A1 | NOVEL BIS(ARYLOXYALKYL) ESTERS OF AROMATIC POLYCARBOXYLIC ACIDS AND METHOD OF PREPARATION | ETHOX CHEMICALS, LLC | 2014-01-30 | — | — | US | disclosed |
| US-20120100323-A1 | Novel bis(ARYLOXYALKYL) esters of aromatic polycarboxylic acids and method of preparation | ETHOX CHEMICALS, LLC | 2012-04-26 | — | — | US | disclosed |
| US-20120100323-A1 | Novel bis(ARYLOXYALKYL) esters of aromatic polycarboxylic acids and method of preparation | ETHOX CHEMICALS, LLC | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140031578-A1 | NOVEL BIS(ARYLOXYALKYL) ESTERS OF AROMATIC POLYCARBOXYLIC ACIDS AND METHOD OF PREPARATION | AHR, AR, ARNT | ALDH1A1 172/4885KDM4E 1017/4885HPGD 1275/4885 |
| US-20180037535-A1 | NOVEL BIS(ARYLOXYALKYL) ESTERS OF AROMATIC POLYCARBOXYLIC ACIDS AND METHOD OF PREPARATION | AHR, AR, ARNT | ALDH1A1 187/4885KDM4E 1009/4885HPGD 1264/4885 |
| US-20120100323-A1 | Novel bis(ARYLOXYALKYL) esters of aromatic polycarboxylic acids and method of preparation | AHR, AR, ARNT | ALDH1A1 187/4885KDM4E 1009/4885HPGD 1264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.