Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | P4HB | P07237 | 5/20 | 0.39 |
| ▸ | FASN | P49327 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3431718 | 0.80 | ALDH5A1 (0.50) | CA12CA1CA2CA6CA9 | |
| SCHEMBL669455 | 0.80 | CA12 (0.50) | CA12CA1CA2CA6CA9 | |
| SCHEMBL3691262 | 0.73 | SLC22A6 (0.53) | KDM4EMEN1NFKB1NFKB2KMT2A | |
| SCHEMBL3434424 | 0.72 | ALDH1A1 (0.46) | ALDH1A1MAPTMEN1NPC1PKM | |
| SCHEMBL30495832 | 0.72 | AKT1 (0.59) | CA12CA1CA2CA6CA9 | |
| SCHEMBL27810318 | 0.72 | AKT1 (0.59) | CA12CA1CA2CA6CA9 | |
| SCHEMBL3948258 | 0.71 | NPC1 (0.48) | CA12CA1CA2CA6CA9 | |
| SCHEMBL3948262 | 0.71 | NPC1 (0.48) | CA12CA1CA2CA6CA9 | |
| SCHEMBL3948261 | 0.71 | NPC1 (0.48) | CA12CA1CA2CA6CA9 | |
| SCHEMBL6692316 | 0.70 | AKT1 (0.42) | CA12CA1CA2CA6CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010068935-A2 | SMALL MOLECULE IMMUNOMODULATORS FOR ALZHEIMER'S DISEASE | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2010-06-17 | — | — | WO | disclosed |