SCHEMBL343355

SCHEMBL343355

CNc1ccc(N)cc1S(=O)(=O)O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 1/20 0.65
ALDH1A1 P00352 6/20 0.62
TDP1 Q9NUW8 4/20 0.62
RECQL P46063 3/20 0.62
L3MBTL1 Q9Y468 3/20 0.62
KDM4E B2RXH2 2/20 0.62
POLB P06746 2/20 0.62
GAA P10253 2/20 0.62
MAPT P10636 2/20 0.62
CASP6 P55212 2/20 0.62
MEN1 O00255 1/20 0.62
KMT2A Q03164 1/20 0.62
ELAVL1 Q15717 1/20 0.62
NSD2 O96028 1/20 0.61
APEX1 P27695 1/20 0.61
APOBEC3A P31941 1/20 0.61
APOBEC3G Q9HC16 1/20 0.61
NT5E P21589 3/20 0.52
HSD17B10 Q99714 5/20 0.52
TSHR P16473 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7564333 0.85 RAPGEF4 (0.51) RAPGEF4ALDH1A1TDP1RECQLL3MBTL1
SCHEMBL9627720 0.85 RAPGEF4 (0.80) RAPGEF4ALDH1A1TDP1RECQLL3MBTL1
SCHEMBL10635283 0.81 RAPGEF4 (0.44) RAPGEF4ALDH1A1TDP1RECQLL3MBTL1
Hydrochloric Acid SCHEMBL27969718 0.81 RAPGEF4 (0.65) RAPGEF4ALDH1A1TDP1RECQLL3MBTL1
SCHEMBL3830815 0.81 RAPGEF4 (0.59) RAPGEF4ALDH1A1TDP1RECQLL3MBTL1
SCHEMBL9083398 0.81 RAPGEF4 (0.59) RAPGEF4ALDH1A1TDP1RECQLL3MBTL1
SCHEMBL9189649 0.80 RAPGEF4 (0.97) RAPGEF4ALDH1A1TDP1RECQLL3MBTL1
SCHEMBL16673108 0.80 RAPGEF4 (0.63) RAPGEF4ALDH1A1TDP1RECQLL3MBTL1
SCHEMBL9711529 0.80 RAPGEF4 (0.58) RAPGEF4ALDH1A1TDP1RECQLL3MBTL1
SCHEMBL9711561 0.80 RAPGEF4 (0.58) RAPGEF4ALDH1A1TDP1RECQLL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021062277-A1 FUNCTIONALIZED POLYMER FOR BATTERY APPLICATIONS CONAMIX INC. (US) 2021-04-01 WO disclosed
WO-2020263761-A1 IRON(III) AND GALLIUM(III) METAL ORGANIC POLYHEDRA, METHODS OF MAKING SAME, AND USES THEREOF THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2020-12-30 WO disclosed
EP-2441806-B1 PORPHYRAZINE COLORING MATTER, INK COMPOSITION, RECORDING METHOD, AND COLORED OBJECT NIPPON KAYAKU KK (JP) 2017-09-06 EP disclosed
EP-2463345-B1 Ink composition, recording method using the same and recorded material SEIKO EPSON CORP (JP) 2017-01-18 EP disclosed
EP-3015516-A1 INK COMPOSITION, INK JET RECORDING METHOD USING SAME, AND COLORED MATERIAL Nippon Kayaku Kabushiki Kaisha (JP) 2016-05-04 EP disclosed
EP-2420538-B1 PORPHYRAZINE DYE, INK COMPOSITION CONTAINING SAME, AND COLORED BODY NIPPON KAYAKU KK (JP) 2015-04-22 EP disclosed
US-8876273-B2 Ink composition, ink jet recording method using the same and recorded material SEIKO EPSON CORPORATION (JP) 2014-11-04 US disclosed
US-8857965-B2 Ink compostion, recording method using the same and recorded material SEIKO EPSON CORPORATION (JP) 2014-10-14 US disclosed
US-8790458-B2 Ink set and droplet ejection apparatus using the ink set SEIKO EPSON CORPORATION (JP) 2014-07-29 US disclosed
US-8657433-B2 Porphyrazine coloring matter, ink composition, recording method, and colored object NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2014-02-25 US disclosed
US-5532362-A COLORFAST, HIGH TINCTORIAL STRENGTH HOECHST CELANESE CORPORATION (US) 1996-07-02 US disclosed
EP-0694588-A1 Triphendioxazine reactive dyes, preparation and use thereof BAYER AG (DE) 1996-01-31 EP disclosed
WO-1994021646-A1 FIBER-REACTIVE TRIPHENODIOXAZINE DYES HOECHST CELANESE CORPORATION (US) 1994-09-29 WO disclosed
EP-0387579-B1 Duplicated reactive dyes BASF AG (DE) 1993-11-18 EP disclosed
US-5175262-A High fixation efficiency on cotton BASF AKTIENGESELLSCHAFT (DE) 1992-12-29 US disclosed
EP-0316722-A2 Water soluble azo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1989-05-24 EP disclosed
US-4604459-A Triphendioxazine reactive dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1986-08-05 US disclosed
EP-0170838-A2 Reactive dyes of the dioxazine-type, their preparation and use BAYER AG (DE) 1986-02-12 EP disclosed
EP-0097119-A2 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1983-12-28 EP disclosed
US-4051134-A Reactive dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1977-09-27 US disclosed