SCHEMBL3830815

SCHEMBL3830815

CC(=O)Nc1ccc(N)cc1S(=O)(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 1/20 0.59
ALDH1A1 P00352 4/20 0.57
CASP6 P55212 3/20 0.57
POLB P06746 3/20 0.57
MAPT P10636 3/20 0.57
TDP1 Q9NUW8 3/20 0.57
KDM4E B2RXH2 2/20 0.57
GAA P10253 2/20 0.57
RECQL P46063 2/20 0.57
L3MBTL1 Q9Y468 2/20 0.57
MEN1 O00255 1/20 0.57
KMT2A Q03164 1/20 0.57
ELAVL1 Q15717 1/20 0.57
NSD2 O96028 1/20 0.56
APEX1 P27695 1/20 0.56
APOBEC3A P31941 1/20 0.56
APOBEC3G Q9HC16 1/20 0.56
NPC1 O15118 2/20 0.54
HSD17B10 Q99714 2/20 0.49
NT5E P21589 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9459478 0.87 NPC1 (0.50) RAPGEF4ALDH1A1CASP6POLBMAPT
SCHEMBL16673108 0.86 RAPGEF4 (0.63) RAPGEF4ALDH1A1CASP6POLBMAPT
SCHEMBL11338003 0.85 RAPGEF4 (0.76) RAPGEF4ALDH1A1CASP6POLBMAPT
SCHEMBL6848386 0.84 RAPGEF4 (0.54) RAPGEF4ALDH1A1CASP6POLBMAPT
SCHEMBL8986206 0.82 ALDH1A1 (0.59) RAPGEF4ALDH1A1CASP6POLBMAPT
SCHEMBL11818286 0.82 RAPGEF4 (0.58) RAPGEF4ALDH1A1CASP6POLBMAPT
SCHEMBL16015147 0.81 KMT2A (0.48) ALDH1A1CASP6POLBMAPTTDP1
SCHEMBL343355 0.81 RAPGEF4 (0.65) RAPGEF4ALDH1A1CASP6POLBMAPT
SCHEMBL9054973 0.81 RAPGEF4 (0.60) RAPGEF4ALDH1A1CASP6POLBMAPT
SCHEMBL8947534 0.81 CA2 (0.44) RAPGEF4ALDH1A1CASP6POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0333656-A1 Reactive dyes, process for their preparation and their use CIBA-GEIGY AG (CH) 1989-09-20 EP claimed
EP-1521808-B1 COMPOSITIONS AND INKS CONTAINING DISAZO DYES FUJIFILM IMAGING COLORANTS LTD (GB) 2012-08-01 EP disclosed
EP-1614719-B1 AZO COMPOUND AND SALT THEREOF NIPPON KAYAKU KK (JP) 2009-09-09 EP disclosed
US-7530685-B2 Trisazo dyes for inks for ink jet printing FUJIFILM IMAGING COLORANTS LIMITED (GB) 2009-05-12 US disclosed
US-7481522-B2 Compositions and inks containing disazo dyes FUJIFILM IMAGING COLORANTS LIMITED (GB) 2009-01-27 US disclosed
US-7481522-B2 Compositions and inks containing disazo dyes FUJIFILM IMAGING COLORANTS LIMITED (GB) 2009-01-27 US disclosed
US-7481522-B2 Compositions and inks containing disazo dyes FUJIFILM IMAGING COLORANTS LIMITED (GB) 2009-01-27 US disclosed
US-20080233289-A1 diazo dyes used as ink jet printing inks or for dyeing nitrogen-containing or hydroxy-group-containing organic substrates such as leather, fibers, natural or synthetic polyamides, regenerated cellulose or textiles such as cotton; colorfastness CLARIANT FINANCE (BVI) LIMITED (VG) 2008-09-25 US disclosed
CN-100419029-C Azo compound and salt thereof NIPPON KAYAKU KK (JP) 2008-09-17 CN disclosed
US-7304147-B2 Azo compound and salt thereof NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2007-12-04 US disclosed
EP-0459950-A1 Stabilisation of dyes on polyamide fibres CIBA-GEIGY AG (CH) 1991-12-04 EP disclosed
US-5021557-A Copper-containing formazan dye, colorfast blue shades on cellulose CIBA-GEIGY CORPORATION (US) 1991-06-04 US disclosed
EP-0333656-A1 Reactive dyes, process for their preparation and their use CIBA-GEIGY AG (CH) 1989-09-20 EP disclosed
US-4602084-A Monoazo dyes containing a 4-substituted-2-azo-1,1'-diphenylsulfone component CIBA-GEIGY CORPORATION (US) 1986-07-22 US disclosed
EP-0101408-B1 MONOAZO DYESTUFFS, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1986-05-07 EP disclosed
EP-0101408-A1 Monoazo dyestuffs, their preparation and their use CIBA-GEIGY AG (CH) 1984-02-22 EP disclosed
EP-0018939-B1 1:2 METAL COMPLEX DYESTUFFS OF AZOMETHINES, PROCESS FOR THEIR PREPARATION AND PROCESS FOR DYEING AND PRINTING BY USING THESE DYESTUFFS CIBA-GEIGY AG (CH) 1983-10-05 EP disclosed
US-4315854-A Chromium and cobalt complex amino hydroxy azomethine dyes CIBA-GEIGY CORPORATION (US) 1982-02-16 US disclosed
EP-0018939-A1 1:2 Metal complex dyestuffs of azomethines, process for their preparation and process for dyeing and printing by using these dyestuffs CIBA-GEIGY AG (CH) 1980-11-12 EP disclosed
US-4138558-A Anthraquinone compounds NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1979-02-06 US disclosed