SCHEMBL3433691

SCHEMBL3433691

Cc1cccc(C)c1OCCCNCCC(C)O

nearest known ligand 0.60

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.60
ALDH1A1 P00352 1/20 0.60
SCN8A Q9UQD0 17/20 0.56
SCN2A Q99250 1/20 0.49
HTR1A P08908 1/20 0.48
ADRA1D P25100 1/20 0.48
ADRA1A P35348 1/20 0.48
ADRA1B P35368 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3402626 0.95 KDM4E (0.54) KDM4EALDH1A1SCN8ASCN2AHTR1A
SCHEMBL15346294 0.86 LMNA (0.58) KDM4EALDH1A1SCN8A
SCHEMBL1195765 0.81 KDM4E (0.62) KDM4EALDH1A1SCN8ASCN2AHTR1A
SCHEMBL1195323 0.81 KDM4E (0.62) KDM4EALDH1A1SCN8ASCN2AHTR1A
SCHEMBL1194750 0.81 KDM4E (0.62) KDM4EALDH1A1SCN8ASCN2AHTR1A
SCHEMBL3433693 0.78 SCN8A (0.55) KDM4EALDH1A1SCN8ASCN2A
SCHEMBL15346452 0.77 ALDH1A1 (0.80) KDM4EALDH1A1SCN8ASCN2AHTR1A
Hydrochloric Acid SCHEMBL1196039 0.76 ALDH1A1 (0.78) KDM4EALDH1A1SCN8ASCN2AHTR1A
SCHEMBL15346418 0.75 ALDH1A1 (0.64) KDM4EALDH1A1SCN8AHTR1AADRA1D
SCHEMBL23897365 0.74 SCN8A (0.54) KDM4EALDH1A1SCN8AHTR1AADRA1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2247571-A2 DERIVATIVES OF AMINOALKANOLS, METHOD OF OBTAINING OF AMINOALKANOLS AND THEIR USE Uniwersytet Jagiellonski (PL) 2010-11-10 EP disclosed
WO-2009093916-A2 DERIVATIVES OF AMINOALKANOLS, METHOD OF OBTAINING AMINOALKANOLS AND THEIR USE UNIWERSYTET JAGIELLONSKI (PL) 2009-07-30 WO disclosed