Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 18/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1195269 | 0.95 | SCN8A (0.49) | SCN8AKDM4EALDH1A1SCN2A | |
| SCHEMBL15346447 | 0.86 | KDM4E (0.50) | SCN8AKDM4EALDH1A1SCN2A | |
| SCHEMBL15346294 | 0.85 | LMNA (0.58) | SCN8AKDM4EALDH1A1 | |
| SCHEMBL1195323 | 0.80 | KDM4E (0.62) | SCN8AKDM4EALDH1A1SCN2A | |
| SCHEMBL1194750 | 0.80 | KDM4E (0.62) | SCN8AKDM4EALDH1A1SCN2A | |
| SCHEMBL1195765 | 0.80 | KDM4E (0.62) | SCN8AKDM4EALDH1A1SCN2A | |
| SCHEMBL15346418 | 0.80 | ALDH1A1 (0.64) | SCN8AKDM4EALDH1A1 | |
| SCHEMBL3433691 | 0.78 | KDM4E (0.60) | SCN8AKDM4EALDH1A1SCN2A | |
| SCHEMBL15346302 | 0.75 | ALDH1A1 (0.58) | SCN8AKDM4EALDH1A1 | |
| SCHEMBL15346309 | 0.75 | ALDH1A1 (0.58) | SCN8AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8841347-B2 | Derivatives of aminoalkanols, method of obtaining of aminoalkanols and their use | UNIWERSYTET JAGIELLONSKI (PL) | 2014-09-23 | — | — | US | claimed |
| US-8633251-B2 | Derivatives of aminoalkanols, method of obtaining of aminoalkanols and their use | UNIWERSYTET JAGIELLONSKI (PL) | 2014-01-21 | — | — | US | claimed |
| US-20130289118-A1 | DERIVATIVES OF AMINOALKANOLS, METHOD OF OBTAINING OF AMINOALKANOLS AND THEIR USE | UNIWERSYTET JAGIELLONSKI (PL) | 2013-10-31 | — | — | US | claimed |
| EP-2247571-A2 | DERIVATIVES OF AMINOALKANOLS, METHOD OF OBTAINING OF AMINOALKANOLS AND THEIR USE | Uniwersytet Jagiellonski (PL) | 2010-11-10 | — | — | EP | disclosed |
| WO-2009093916-A2 | DERIVATIVES OF AMINOALKANOLS, METHOD OF OBTAINING AMINOALKANOLS AND THEIR USE | UNIWERSYTET JAGIELLONSKI (PL) | 2009-07-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130289118-A1 | DERIVATIVES OF AMINOALKANOLS, METHOD OF OBTAINING OF AMINOALKANOLS AND THEIR USE | SCN1A, SCN3A, ACHE | SCN8A 7/4885KDM4E 2309/4885ALDH1A1 461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.