Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RHOA | P61586 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1553367 | 0.84 | PTPN1 (0.51) | KMT2APTPN1HTTLMNAHTR1A | |
| SCHEMBL1553823 | 0.84 | RHOA (0.55) | PKMKLK7RXFP1HTTLMNA | |
| SCHEMBL2467773 | 0.78 | HTR1A (0.60) | KMT2AHTR1ADRD2DRD4HTR2A | |
| SCHEMBL1554138 | 0.76 | PTPN1 (0.60) | KMT2APTPN1LMNAALDH1A1POLB | |
| SCHEMBL192930 | 0.74 | ALDH1A1 (0.69) | PTPN1RAB9AHTTLMNAALDH1A1 | |
| SCHEMBL1552820 | 0.69 | F10 (0.48) | DRD2DRD3KDM4E | |
| SCHEMBL21061548 | 0.69 | GAA (0.56) | SLC18A3KMT2APKMKLK7RXFP1 | |
| SCHEMBL30435357 | 0.69 | GAA (0.56) | SLC18A3KMT2APKMKLK7RXFP1 | |
| SCHEMBL7302157 | 0.69 | ALDH1A1 (0.62) | SLC18A3KMT2APKMKLK7RXFP1 | |
| SCHEMBL29259533 | 0.69 | RHOA (0.78) | RHOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010048673-A1 | MODULATION OF CELLULAR DIFFERENTIATION AND USES THEREFOR | MURDOCH CHILDRENS RESEARCH INSTITUTE (AU) | 2010-05-06 | — | — | WO | disclosed |