Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 5/20 | 0.38 |
| ▸ | KIF20A | O95235 | 3/20 | 0.38 |
| ▸ | CLK1 | P49759 | 5/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3435941 | 0.72 | DYRK1A (0.50) | DYRK1AKIF20ACLK1 | |
| SCHEMBL2725122 | 0.67 | KIF20A (0.45) | DYRK1AKIF20ACLK1 | |
| SCHEMBL2724759 | 0.66 | DYRK1A (0.49) | DYRK1AKIF20ACLK1NR4A2 | |
| SCHEMBL3434452 | 0.65 | DYRK1A (0.56) | DYRK1AKIF20ACLK1NR4A2 | |
| SCHEMBL3434269 | 0.65 | DYRK1A (0.60) | DYRK1AKIF20ACLK1NR4A2 | |
| SCHEMBL15907803 | 0.64 | DYRK1A (0.67) | DYRK1AKIF20ACLK1NR4A2 | |
| SCHEMBL2725493 | 0.64 | DYRK1A (0.67) | DYRK1AKIF20ACLK1NR4A2 | |
| SCHEMBL2725494 | 0.64 | DYRK1A (0.67) | DYRK1AKIF20ACLK1NR4A2 | |
| SCHEMBL2728478 | 0.64 | DYRK1A (0.67) | DYRK1AKIF20ACLK1NR4A2 | |
| SCHEMBL2728481 | 0.64 | DYRK1A (0.67) | DYRK1AKIF20ACLK1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2266562-A1 | Use of derivatives of indoles for the treatment of cancer | Centre National de la Recherche Scientifique (FR) | 2010-12-29 | — | — | EP | claimed |