Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 10/20 | 0.58 |
| ▸ | BCHE | P06276 | 2/20 | 0.50 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8756173 | 0.98 | ACHE (0.59) | ACHEBCHEAPOBEC3AAPOBEC3GALDH1A1 | |
| Bromide SCHEMBL6956206 | 0.96 | ACHE (0.62) | ACHEBCHEAPOBEC3AAPOBEC3GALDH1A1 | |
| Hydrochloric Acid SCHEMBL716655 | 0.96 | ACHE (0.58) | ACHEBCHEAPOBEC3AAPOBEC3GALDH1A1 | |
| SCHEMBL7898036 | 0.80 | ACHE (0.46) | ACHEBCHEAPOBEC3AAPOBEC3GALDH1A1 | |
| SCHEMBL9327504 | 0.78 | ACHE (0.42) | ACHEBCHEALDH1A1MAPK1SMN1; SMN2 | |
| Iodide SCHEMBL29602377 | 0.76 | ACHE (0.40) | ACHEBCHEAPOBEC3AAPOBEC3GALDH1A1 | |
| Hydrochloric Acid SCHEMBL27711002 | 0.75 | ACHE (0.54) | ACHEBCHEAPOBEC3AAPOBEC3GALDH1A1 | |
| Hydrochloric Acid SCHEMBL4903472 | 0.75 | ACHE (0.51) | ACHEBCHEALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL27047852 | 0.75 | ACHE (0.42) | ACHEBCHEAPOBEC3AAPOBEC3GALDH1A1 | |
| Iodide SCHEMBL11335491 | 0.75 | ALDH1A1 (0.44) | ACHEBCHEAPOBEC3AAPOBEC3GALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100004202-A1 | Quaternary ammonium-functionalized-POSS compounds | NDSU RESEARCH FOUNDATION | 2010-01-07 | — | — | US | disclosed |
| EP-0251577-B1 | Ammonium salt solution as electrolyte for electrolytic capacitors | MITSUBISHI PETROCHEMICAL CO (JP) | 1994-05-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004202-A1 | Quaternary ammonium-functionalized-POSS compounds | ARG1, SAE1, RBX1 | ACHE 1569/4885BCHE 3970/4885APOBEC3A 3236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.