SCHEMBL3434656

SCHEMBL3434656

CCC(C)(C)c1cc(CO)cc(OC)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.39
DAO P14920 1/20 0.38
CALM1 P0DP23 2/20 0.37
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
GABRA1 P14867 1/20 0.35
GABRG2 P18507 1/20 0.35
GABRB3 P28472 1/20 0.35
GABRA3 P34903 1/20 0.35
GABRA2 P47869 1/20 0.35
GABRB2 P47870 1/20 0.35
CNR2 P34972 3/20 0.34
CNR1 P21554 2/20 0.34
MAPT P10636 2/20 0.34
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
GRIN2D O15399 1/20 0.34
GRIN3B O60391 1/20 0.34
GRIN1 Q05586 1/20 0.34
GRIN2A Q12879 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20285804 0.84 CA1 (0.42) PTGS2DAOCALM1CA1CA2
SCHEMBL845798 0.83 ALDH1A1 (0.50) PTGS2CA1CA2CNR2CNR1
SCHEMBL3948413 0.79 RXRA (0.49) DAO
SCHEMBL4567351 0.79 CNR2 (0.39) PTGS2DAOCALM1CNR2CNR1
SCHEMBL17124420 0.77 DAO (0.40) PTGS2DAOCALM1CA1CA2
SCHEMBL17124419 0.77 CYP19A1 (0.38) PTGS2DAOCALM1CA1CA2
SCHEMBL65276 0.77 ALDH1A1 (0.58) PTGS2DAOCALM1MAPTGRIN2D
SCHEMBL1621101 0.77 DAO (0.53) PTGS2DAOCALM1GABRA1GABRG2
SCHEMBL15506135 0.75 ALDH1A1 (0.50) CALM1CA1CA2CNR2CNR1
SCHEMBL20288257 0.75 NPC1 (0.36) CA1CA2CNR2CNR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120094235-A1 ACTINIC-RAY- OR RADIATION-SENSITIVE RESIN COMPOSITION AND METHOD OF FORMING PATTERN USING THE COMPOSITION FUJIFILM CORPORATION (JP) 2012-04-19 US disclosed