SCHEMBL65276

SCHEMBL65276

COc1cc(CO)cc(OC)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.58
DAO P14920 1/20 0.49
AKR1B1 P15121 1/20 0.48
CYP19A1 P11511 1/20 0.47
CALM1 P0DP23 4/20 0.46
MAPT P10636 1/20 0.45
GRIN2D O15399 1/20 0.45
GRIN3B O60391 1/20 0.45
GRIN1 Q05586 1/20 0.45
GRIN2A Q12879 1/20 0.45
GRIN2B Q13224 1/20 0.45
GRIN2C Q14957 1/20 0.45
GRIN3A Q8TCU5 1/20 0.45
CYP1A1 P04798 1/20 0.44
CYP1B1 Q16678 1/20 0.44
CYP4F2 P78329 1/20 0.42
CYP4A11 Q02928 1/20 0.42
PTGS2 P35354 1/20 0.42
TSHR P16473 1/20 0.42
CYP3A4 P08684 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28123040 0.97 ALDH1A1 (0.55) ALDH1A1DAOAKR1B1CYP19A1CALM1
SCHEMBL1621101 0.95 DAO (0.53) ALDH1A1DAOAKR1B1CYP19A1CALM1
SCHEMBL920598 0.93 ALDH1A1 (0.50) ALDH1A1DAOAKR1B1CYP19A1CALM1
SCHEMBL8353978 0.91 ALDH1A1 (0.48) ALDH1A1DAOAKR1B1CYP19A1CALM1
SCHEMBL11791322 0.89 CALM1 (0.55) ALDH1A1AKR1B1CYP19A1CALM1
SCHEMBL24951300 0.87 MAOB (0.46) ALDH1A1DAOAKR1B1CALM1
SCHEMBL8264227 0.87 CALM1 (0.47) ALDH1A1DAOAKR1B1CYP19A1CALM1
SCHEMBL29389280 0.86 CALM1 (0.61) ALDH1A1DAOAKR1B1CALM1MAPT
SCHEMBL1650366 0.86 CALM1 (0.61) ALDH1A1DAOAKR1B1CALM1MAPT
SCHEMBL8228443 0.86 DAO (0.47) ALDH1A1DAOAKR1B1CYP19A1CALM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 670 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559582-B2 Polyacrylate polymer BASF SE (DE) 2026-02-24 US claimed
CN-115073484-B Extraction and separation method of active ingredients of Zhuang medicine garden balsam stem 广西民族大学 2024-05-24 CN claimed
CN-115819221-B Preparation method of (R) -2-hydroxymethyl propionic acid and (S) -2-hydroxymethyl propionic acid 上海馨远医药科技有限公司 2024-05-10 CN claimed
CN-117964834-A Polyacrylate polymers 巴斯夫欧洲公司 2024-05-03 CN claimed
CN-111886233-B Triazolone derivatives or salts thereof and pharmaceutical compositions containing the same 柳韩洋行 2024-01-02 CN claimed
US-11780830-B2 Triazolone derivatives or salts thereof and pharmaceutical compositions comprising the same YUHAN CORPORATION (KR) 2023-10-10 US claimed
CN-115819221-A Preparation method of (R) -2-hydroxymethyl propionic acid and (S) -2-hydroxymethyl propionic acid 上海馨远医药科技有限公司 2023-03-21 CN claimed
CN-114621044-A Method for preparing bibenzyl compound 中国科学院大连化学物理研究所 2022-06-14 CN claimed
EP-3898730-A1 POLYACRYLATE POLYMER BASF SE (DE) 2021-10-27 EP claimed
US-20210317110-A1 TRIAZOLONE DERIVATIVES OR SALTS THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME YUHAN CORPORATION (KR) 2021-10-14 US claimed
WO-2004041201-A2 BENZOFURAN COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS C VIRAL INFECTIONS AND ASSOCIATED DISEASES VIROPHARMA INCORPORATED (US) 2004-05-21 WO claimed
US-6620823-B2 Antiinflammatory agents; rheumatic disorders BRISTOL-MYERS SQUIBB PHARME COMPANY 2003-09-16 US claimed
EP-1341503-A2 AGENT AND METHOD FOR DYEING KERATIN FIBRES Wella Aktiengesellschaft (DE) 2003-09-10 EP claimed
US-20030041391-A1 Agent and method for dyeing keratin fibres Wella GmbH (DE) 2003-03-06 US claimed
WO-2002047633-A2 AGENT AND METHOD FOR DYEING KERATIN FIBRES WELLA AKTIENGESELLSCHAFT (DE) 2002-06-20 WO claimed
US-6319310-B1 FOR ACOUSTIC INK JET PRINTING; TRANSPARENCY, GLOSS, CREASE RESISTANCE XEROX CORPORATION 2001-11-20 US claimed
EP-0674232-B1 Recording sheets XEROX CORP (US) 2000-05-31 EP claimed
US-5922117-A Ink compositions containing alcohols XEROX CORPORATION (US) 1999-07-13 US claimed
US-5663022-A Recording sheets XEROX CORPORATION (US) 1997-09-02 US claimed
EP-0674232-A2 Recording sheets XEROX CORPORATION (US) 1995-09-27 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210317110-A1 TRIAZOLONE DERIVATIVES OR SALTS THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME SLC10A1, VAT1, LIPC ALDH1A1 371/4885DAO 3324/4885AKR1B1 499/4885
US-11780830-B2 Triazolone derivatives or salts thereof and pharmaceutical compositions comprising the same SLC10A1, VAT1, LIPC ALDH1A1 371/4885DAO 3324/4885AKR1B1 499/4885
US-12559582-B2 Polyacrylate polymer SAAL1, ATXN2L, VCL ALDH1A1 508/4885DAO 1580/4885AKR1B1 1525/4885
US-20030041391-A1 Agent and method for dyeing keratin fibres KRT18, AKR7A2, ADH5 ALDH1A1 27/4885DAO 78/4885AKR1B1 14/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.