Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.47 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.47 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22954025 | 0.80 | ALDH1A1 (0.44) | PLK1ALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL3279594 | 0.79 | MAPT (0.67) | ALDH1A1TDP1CYP3A4TSHRHPGD | |
| SCHEMBL3279016 | 0.78 | MAPT (0.50) | ALDH1A1TDP1CYP3A4TSHRHPGD | |
| SCHEMBL3286185 | 0.78 | MAPT (0.50) | ALDH1A1TDP1CYP3A4TSHRHPGD | |
| SCHEMBL8855525 | 0.76 | PLK1 (0.53) | PLK1ALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL3283183 | 0.75 | PKM (0.50) | MAPTMAPK1PKM | |
| SCHEMBL22954108 | 0.74 | MAPT (0.60) | ALDH1A1MAPTMAPK1PKMPOLB | |
| SCHEMBL22954114 | 0.74 | PKM (0.49) | PKM | |
| SCHEMBL11867676 | 0.73 | ALDH1A1 (0.43) | PLK1ALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL22954616 | 0.73 | PLK1 (0.50) | PLK1ALDH1A1TDP1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7807821-B1 | Method for the synthesis of nucleic acid without protecting base moiety | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2010-10-05 | — | — | US | claimed |
| EP-1721908-A1 | NOVEL METHOD OF SYNTHESIZING NUCLEIC ACID WITHOUT PROTECTING NUCLEOTIDE BASES | Japan Science and Technology Agency (JP) | 2006-11-15 | — | — | EP | claimed |
| EP-3862431-B1 | METHOD FOR PRODUCING HAIRPIN SINGLE-STRAND RNA MOLECULES | TORAY INDUSTRIES (JP) | 2024-06-26 | — | — | EP | disclosed |
| US-20240110186-A1 | METHOD OF PRODUCING HAIRPIN SINGLE-STRANDED RNA MOLECULES | TORAY INDUSTRIES, INC. (JP) | 2024-04-04 | — | — | US | disclosed |
| US-11891602-B2 | Method of producing hairpin single-stranded RNA molecules | TORAY INDUSTRIES, INC. (JP) | 2024-02-06 | — | — | US | disclosed |
| CN-116829567-A | Oligonucleotide prodrugs based on cyclic disulfide modified phosphates | 阿尔尼拉姆医药品有限公司 | 2023-09-29 | — | — | CN | disclosed |
| US-11760701-B2 | Difluoromethoxylation and trifluoromethoxylation compositions and methods for synthesizing same | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YROK (US) | 2023-09-19 | — | — | US | disclosed |
| US-20210317495-A1 | METHOD OF PRODUCING HAIRPIN SINGLE-STRANDED RNA MOLECULES | TORAY INDUSTRIES, INC. (JP) | 2021-10-14 | — | — | US | disclosed |
| EP-3862431-A1 | METHOD FOR PRODUCING HAIRPIN SINGLE-STRAND RNA MOLECULES | Toray Industries, Inc. (JP) | 2021-08-11 | — | — | EP | disclosed |
| CN-112673102-A | Preparation method of hairpin type single-stranded RNA molecule | 东丽株式会社 | 2021-04-16 | — | — | CN | disclosed |
| US-20210032181-A1 | DIFLUOROMETHOXYLATION AND TRIFLUOROMETHOXYLATION COMPOSITIONS AND METHODS FOR SYNTHESIZING SAME | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2021-02-04 | — | — | US | disclosed |
| US-7807821-B1 | Method for the synthesis of nucleic acid without protecting base moiety | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2010-10-05 | — | — | US | disclosed |
| US-7807821-B1 | Method for the synthesis of nucleic acid without protecting base moiety | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2010-10-05 | — | — | US | disclosed |
| EP-1721908-A1 | NOVEL METHOD OF SYNTHESIZING NUCLEIC ACID WITHOUT PROTECTING NUCLEOTIDE BASES | Japan Science and Technology Agency (JP) | 2006-11-15 | — | — | EP | disclosed |
| EP-0739898-B1 | Phosphonomonoester nucleic acids, methods for their preparation and their use | AVENTIS PHARMA GMBH (DE) | 2001-09-26 | — | — | EP | disclosed |
| CN-1060781-C | Phosphonootropic monoester nucleic acids, process for their preparation and their use | HOECHST AG (DE) | 2001-01-17 | — | — | CN | disclosed |
| US-6127346-A | FOR THE TREATMENT OF VIRUSES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-10-03 | — | — | US | disclosed |
| US-5874553-A | ANTIBODIES; INHIBITOR OF GENE EXPRESSION | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-02-23 | — | — | US | disclosed |
| CN-1138588-A | Phosphonootropic monoester nucleic acids, process for their preparation and their use | HOECHST AG (DE) | 1996-12-25 | — | — | CN | disclosed |
| EP-0739898-A2 | Phosphonomonoester nucleic acids, methods for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-10-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210032181-A1 | DIFLUOROMETHOXYLATION AND TRIFLUOROMETHOXYLATION COMPOSITIONS AND METHODS FOR SYNTHESIZING SAME | AFF2, AFF4, AFF1 | PLK1 2834/4885ALDH1A1 1490/4885TDP1 2207/4885 |
| US-11760701-B2 | Difluoromethoxylation and trifluoromethoxylation compositions and methods for synthesizing same | AFF2, AFF4, AFF1 | PLK1 2834/4885ALDH1A1 1490/4885TDP1 2207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.