SCHEMBL3435183

SCHEMBL3435183

Cc1cc(N=Nc2ccc3ccc(N=Nc4cccc(S(=O)(=O)O)c4)c(N)c3c2O)ccc1[N+](=O)[O-]

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SENP2 Q9HC62 4/20 0.45
SENP1 Q9P0U3 4/20 0.45
SENP3 Q9H4L4 3/20 0.45
SUMO2 P61956 2/20 0.45
SUMO1 P63165 2/20 0.45
SENP7 Q9BQF6 2/20 0.45
ENPP2 Q13822 4/20 0.44
CYP1A2 P05177 2/20 0.41
KMT2A Q03164 4/20 0.40
MAPT P10636 3/20 0.40
MAPK1 P28482 3/20 0.40
GAA P10253 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
PTPN11 Q06124 2/20 0.39
HPGD P15428 2/20 0.38
PTPN1 P18031 1/20 0.38
PTPN6 P29350 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
MEN1 O00255 3/20 0.38
KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3434142 0.89 PTPN11 (0.50) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL3435549 0.86 SENP2 (0.51) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL3434173 0.83 MEN1 (0.47) ENPP2KMT2AMAPTMAPK1TDP1
SCHEMBL3435168 0.83 ENPP2 (0.49) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL16488650 0.82 PTPN11 (0.48) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL3434042 0.79 SENP2 (0.54) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL3434123 0.79 ENPP2 (0.64) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL16488652 0.77 ENPP2 (0.48) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL16488648 0.77 ENPP2 (0.48) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL3434143 0.77 SENP2 (0.56) SENP2SENP1SENP3SUMO2SUMO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8834620-B2 Black disazo dyes, their preparation and use ILFORD IMAGING SWITZERLAND GMBH (CH) 2014-09-16 US disclosed
US-20120090503-A1 BLACK DISAZO DYES, THEIR PREPARATION AND USE ILFORD IMAGING SWITZERLAND GMBH 2012-04-19 US disclosed