SCHEMBL3435549

SCHEMBL3435549

Nc1c(N=Nc2ccc([N+](=O)[O-])cc2)ccc2ccc(N=Nc3cccc(S(=O)(=O)O)c3)c(O)c12

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SENP2 Q9HC62 3/20 0.51
SENP3 Q9H4L4 2/20 0.51
SENP1 Q9P0U3 2/20 0.51
SUMO2 P61956 2/20 0.51
SUMO1 P63165 2/20 0.51
SENP7 Q9BQF6 2/20 0.51
ENPP2 Q13822 4/20 0.50
PTPN11 Q06124 1/20 0.46
CYP1A2 P05177 2/20 0.46
KMT2A Q03164 3/20 0.45
MEN1 O00255 2/20 0.45
MAPT P10636 2/20 0.45
ALDH1A1 P00352 1/20 0.45
LMNA P02545 1/20 0.45
POLB P06746 1/20 0.45
HTT P42858 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
CYP2C9 P11712 2/20 0.43
CYP2C19 P33261 2/20 0.43
HSD17B10 Q99714 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3435168 0.92 ENPP2 (0.49) SENP2SENP3SENP1SUMO2SUMO1
SCHEMBL3435585 0.90 ENPP2 (0.51) SENP2SUMO2SUMO1SENP7ENPP2
SCHEMBL3434123 0.90 ENPP2 (0.64) SENP2SENP3SENP1SUMO2SUMO1
SCHEMBL3434142 0.88 PTPN11 (0.50) SENP2SENP3SENP1SUMO2SUMO1
SCHEMBL3435183 0.86 SENP2 (0.45) SENP2SENP3SENP1SUMO2SUMO1
SCHEMBL3433628 0.86 ALDH1A1 (0.49) ENPP2CYP1A2KMT2AMEN1MAPT
SCHEMBL16488648 0.85 ENPP2 (0.48) SENP2SENP3SENP1SUMO2SUMO1
SCHEMBL3434065 0.85 ENPP2 (0.48) SENP2SENP3SENP1SUMO2SUMO1
SCHEMBL3435541 0.85 MEN1 (0.51) SENP7ENPP2CYP1A2KMT2AMEN1
SCHEMBL31222686 0.85 MEN1 (0.51) SENP7ENPP2CYP1A2KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8834620-B2 Black disazo dyes, their preparation and use ILFORD IMAGING SWITZERLAND GMBH (CH) 2014-09-16 US disclosed
US-20120090503-A1 BLACK DISAZO DYES, THEIR PREPARATION AND USE ILFORD IMAGING SWITZERLAND GMBH 2012-04-19 US disclosed