Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL780091 | 0.81 | NPC1 (0.43) | NPC1RAB9ALMNAMAPK1CASP3 | |
| SCHEMBL20508229 | 0.80 | TSHR (0.32) | NOTUMCYP2C9ALDH1A1CYP3A4HPGD | |
| SCHEMBL2903675 | 0.78 | NPC1 (0.44) | NPC1RAB9ALMNAMAPK1CASP3 | |
| SCHEMBL22004473 | 0.76 | POLB (0.38) | NPC1RAB9ALMNAMAPK1CASP3 | |
| SCHEMBL3239365 | 0.75 | NPC1 (0.48) | NPC1RAB9ALMNAMAPK1CASP3 | |
| SCHEMBL21654203 | 0.75 | MAPT (0.42) | NPC1RAB9ALMNAMAPK1CASP3 | |
| SCHEMBL1542833 | 0.75 | TSHR (0.61) | NPC1RAB9ALMNAMAPK1CASP3 | |
| SCHEMBL23616387 | 0.74 | TRPV1 (0.33) | NPC1RAB9ALMNAMAPK1CASP3 | |
| SCHEMBL846677 | 0.73 | GABRA1 (0.46) | LMNASMN1; SMN2MAPTNOTUMPOLB | |
| SCHEMBL8141537 | 0.73 | ALOX15 (0.52) | MAPK1NOTUMALDH1A1CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120094235-A1 | ACTINIC-RAY- OR RADIATION-SENSITIVE RESIN COMPOSITION AND METHOD OF FORMING PATTERN USING THE COMPOSITION | FUJIFILM CORPORATION (JP) | 2012-04-19 | — | — | US | disclosed |