SCHEMBL846677

SCHEMBL846677

CC(C)(C)c1cc(Br)cc(Br)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.46
GABRB2 P47870 1/20 0.46
POLB P06746 1/20 0.42
HIF1A Q16665 2/20 0.36
CYP2C19 P33261 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
HTR1D P28221 2/20 0.36
TSHR P16473 3/20 0.35
ALDH1A1 P00352 4/20 0.35
TDP1 Q9NUW8 3/20 0.35
HPGD P15428 2/20 0.35
ALOX15 P16050 2/20 0.35
HSD17B10 Q99714 2/20 0.35
RECQL P46063 2/20 0.35
CYP3A4 P08684 2/20 0.35
ALOX12 P18054 1/20 0.35
CASP1 P29466 1/20 0.35
MEN1 O00255 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL190968 0.94 GABRA1 (0.52) GABRA1GABRB2POLBHIF1ACYP2C19
SCHEMBL28241863 0.91 GABRA1 (0.50) GABRA1GABRB2POLBHIF1ACYP2C19
SCHEMBL31071024 0.86 RXRB (0.41) GABRA1GABRB2POLBHIF1ACYP2C19
SCHEMBL18537286 0.84 GABRA1 (0.44) GABRA1GABRB2POLBHIF1ACYP2C19
SCHEMBL34460149 0.84 POLB (0.41) GABRA1GABRB2POLBHIF1ACYP2C19
SCHEMBL23915436 0.84 GABRA1 (0.44) GABRA1GABRB2POLBHIF1ACYP2C19
SCHEMBL29416703 0.84 GABRA1 (0.44) GABRA1GABRB2POLBHIF1ACYP2C19
SCHEMBL2745570 0.84 POLB (0.41) GABRA1GABRB2POLBHIF1ACYP2C19
SCHEMBL25361919 0.82 GABRA1 (0.37) GABRA1GABRB2POLBHIF1ACYP2C19
SCHEMBL1104681 0.82 NOTUM (0.47) GABRA1GABRB2POLBMAPTNOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 636 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119100974-A Conductive two-dimensional supermolecular polymer constructed based on aromatic ring cation-pi action and preparation method thereof 西北工业大学 2024-12-10 CN claimed
CN-119092798-A MOF-based solid electrolyte composite membrane and preparation method and application thereof 浙江大学杭州国际科创中心 2024-12-06 CN claimed
CN-118219636-B Polymer self-adhesive pre-laid waterproof coiled material and preparation method thereof 丽天防水科技有限公司 2024-08-13 CN claimed
CN-118219636-A Polymer self-adhesive pre-laid waterproof coiled material and preparation method thereof 丽天防水科技有限公司 2024-06-21 CN claimed
CN-117143348-A Metal-MOF composite material and preparation method and application thereof 浙江大学杭州国际科创中心 2023-12-01 CN claimed
CN-116554378-A Non-metallocene catalyst, preparation method and application 万华化学集团股份有限公司 2023-08-08 CN claimed
CN-108358795-A One kind is containing tertiary butyl substitution m-Terphenyl structure aromatic diamine monomers and preparation method thereof 常州大学 2018-08-03 CN claimed
US-20260150575-A1 LIGHT-EMITTING ELEMENT, FUSED POLYCYCLIC COMPOUND FOR LIGHT-EMITTING ELEMENT, AND ELECTRONIC DEVICE INCLUDING THE LIGHT-EMITTING ELEMENT SAMSUNG DISPLAY CO., LTD. (KR) 2026-05-28 US disclosed
EP-4742867-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS Samsung Electronics Co., Ltd. (KR) 2026-05-13 EP disclosed
US-20260123177-A1 POLYCYCLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE POLYCYCLIC COMPOUND, ELECTRONIC DEVICE INCLUDING THE LIGHT-EMITTING DEVICE, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO LTD (KR) 2026-04-30 US disclosed
US-12598908-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2026-04-07 US disclosed
EP-4436349-B1 LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE ORGANOMETALLIC COMPOUND SAMSUNG DISPLAY CO LTD (KR) 2026-04-01 EP disclosed
EP-4714959-A1 LIGHT EMITTING ELEMENT, FUSED POLYCYCLIC COMPOUND FOR THE SAME, AND DISPLAY DEVICE INCLUDING THE SAME Samsung Display Co., Ltd. (KR) 2026-03-25 EP disclosed
WO-2009042694-A1 (3-HYDROXY-4-AMINO-BUTAN-2-YL) -3- (2-THIAZOL-2-YL-PYRROLIDINE-1-CARBONYL) BENZAMIDE DERIVATIVES AND RELATED COMPOUNDS AS BETA-SECRETASE INHIBITORS FOR TREATING COMENTIS, INC. (US) 2009-04-02 WO disclosed
WO-2009015369-A2 COMPOUNDS WHICH INHIBIT BETA-SECRETASE ACTIVITY AND METHODS OF USE THEREOF COMENTIS, INC. (US) 2009-01-29 WO disclosed
US-20080124577-A1 Exhibits a light emission color with significantly high purity , highly efficient, highly luminant, and long-lived light emission; high glass transition temperature, heat stability and superior durability CANON KABUSHIKI KAISHA (JP) 2008-05-29 US disclosed
WO-2007064553-A2 THIAZOLE DERIVATIVES AS CXCR3 RECEPTOR MODULATORS MERCK & CO., INC. (US) 2007-06-07 WO disclosed
US-7214668-B2 Phosphonic acid based prodrugs of PMEA and its analogues METABASIS THERAPEUTICS, INC. (US) 2007-05-08 US disclosed
US-20060115678-A1 Aminoanthryl derivative-substituted pyrene compound and organic light-emitting device CANON KABUSHIKI KAISHA (JP) 2006-06-01 US disclosed
US-20040082578-A1 Arylindenopyridines and related therapeutic and prophylactic methods ORTHO-MCNEIL PHARMACEUTICAL, INC. 2004-04-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260150575-A1 LIGHT-EMITTING ELEMENT, FUSED POLYCYCLIC COMPOUND FOR LIGHT-EMITTING ELEMENT, AND ELECTRONIC DEVICE INCLUDING THE LIGHT-EMITTING ELEMENT NR2E3, NR2E1, RER1 GABRA1 2644/4885GABRB2 2701/4885POLB 3785/4885
US-20040082578-A1 Arylindenopyridines and related therapeutic and prophylactic methods ADORA2A, ADORA1, PDE2A GABRA1 500/4885GABRB2 386/4885POLB 4166/4885
US-12598908-B2 Organic electroluminescent materials and devices LBR, OPRD1, LDLR GABRA1 1014/4885GABRB2 929/4885POLB 1215/4885
US-20080124577-A1 Exhibits a light emission color with significantly high purity , highly efficient, highly luminant, and long-lived light emission; high glass transition temperature, heat stability and superior durability LEF1, MAP1LC3A, HSF1 GABRA1 4392/4885GABRB2 4690/4885POLB 4144/4885
US-20060115678-A1 Aminoanthryl derivative-substituted pyrene compound and organic light-emitting device ALAD, PAH, PPOX GABRA1 2220/4885GABRB2 3557/4885POLB 1683/4885
US-20260123177-A1 POLYCYCLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE POLYCYCLIC COMPOUND, ELECTRONIC DEVICE INCLUDING THE LIGHT-EMITTING DEVICE, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE CDH1, CRY2, CRY1 GABRA1 3178/4885GABRB2 2357/4885POLB 3251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.