Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | GRN | P28799 | 1/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3434714 | 0.99 | CNR1 (0.47) | CNR1NPC1RAB9APOLBHPGDS | |
| SCHEMBL1211553 | 0.89 | NPC1 (0.46) | CNR1NPC1RAB9APOLB | |
| SCHEMBL1211209 | 0.84 | ALDH1A1 (0.46) | NPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL31603634 | 0.84 | ALDH1A1 (0.46) | NPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL3434627 | 0.84 | NPC1 (0.49) | NPC1RAB9APOLBSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2443276 | 0.83 | ALDH1A1 (0.45) | NPC1RAB9APOLBSMN1; SMN2GAA | |
| SCHEMBL13426361 | 0.83 | RAB9A (0.44) | NPC1RAB9ASMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL3433865 | 0.83 | NPC1 (0.48) | NPC1RAB9APOLB | |
| SCHEMBL2440949 | 0.80 | DRD2 (0.45) | NPC1RAB9AGAAMAPT | |
| Hydrochloric Acid SCHEMBL2447402 | 0.79 | DRD2 (0.44) | NPC1RAB9AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252605-A2 | LABELLED ANALOGUES OF HALOBENZAMIDES AS MULTIMODAL RADIOPHARMACEUTICALS AND THEIR PRECURSORS | Institut National de la Santé et de la Recherche Médicale (INSERM) (FR) | 2010-11-24 | — | — | EP | disclosed |
| WO-2009095872-A2 | LABELLED ANALOGUES OF HALOBENZAMIDES AS MULTIMODAL RADIOPHARMACEUTICALS AND THEIR PRECURSORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2009-08-06 | — | — | WO | disclosed |