Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 2/20 | 0.58 |
| ▸ | KIF11 | P52732 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ADH1B | P00325 | 1/20 | 0.41 |
| ▸ | ADH1C | P00326 | 1/20 | 0.41 |
| ▸ | ADH1A | P07327 | 1/20 | 0.41 |
| ▸ | ADH7 | P40394 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2393442 | 0.95 | KCNN4 (0.58) | KCNN4KIF11IDO1MEN1KMT2A | |
| SCHEMBL17731635 | 0.86 | KIF11 (0.55) | KCNN4KIF11IDO1CYP3A4MAPT | |
| SCHEMBL3626482 | 0.81 | MEN1 (0.65) | KCNN4KIF11MEN1KMT2ATDP1 | |
| SCHEMBL18797633 | 0.81 | LTA4H (0.57) | CYP3A4ALDH1A1MAOACYP1A2CYP2C9 | |
| SCHEMBL6191803 | 0.81 | KDM1A (0.47) | KCNN4KIF11IDO1CYP1A2CYP2C19 | |
| SCHEMBL9482260 | 0.78 | IDO1 (0.61) | IDO1MEN1KMT2ATHRBTDP1 | |
| SCHEMBL5147853 | 0.77 | CYP3A4 (0.46) | KCNN4IDO1MEN1KMT2ATHRB | |
| SCHEMBL14340670 | 0.77 | KCNN4 (0.65) | KCNN4KIF11ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL12264131 | 0.77 | KIF11 (0.74) | KCNN4KIF11MEN1KMT2ATDP1 | |
| SCHEMBL10703980 | 0.76 | RAB9A (0.50) | KCNN4IDO1MEN1KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2266958-A1 | Antiviral agent | SHIONOGI & CO., LTD. (JP) | 2010-12-29 | — | — | EP | disclosed |