Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 12/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3436558 | 0.85 | KMT2A (0.43) | ALDH1A1SMN1; SMN2OPRK1HSP90AA1HSP90AB1 | |
| SCHEMBL3434498 | 0.84 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2HSP90AA1HSP90AB1MEN1 | |
| SCHEMBL3434342 | 0.84 | MEN1 (0.40) | ALDH1A1SMN1; SMN2OPRK1HSP90AA1HSP90AB1 | |
| SCHEMBL3434295 | 0.84 | CYP1A2 (0.44) | ALDH1A1SMN1; SMN2OPRK1HSP90AA1HSP90AB1 | |
| SCHEMBL3435067 | 0.81 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2OPRK1HSP90AA1HSP90AB1 | |
| SCHEMBL20524606 | 0.79 | OPRK1 (0.41) | ALDH1A1SMN1; SMN2OPRK1MAPT | |
| SCHEMBL3435131 | 0.77 | CYP3A4 (0.46) | ALDH1A1SMN1; SMN2OPRK1MEN1KMT2A | |
| SCHEMBL20605140 | 0.75 | HRH4 (0.53) | SMN1; SMN2 | |
| SCHEMBL29969981 | 0.75 | HRH4 (0.53) | SMN1; SMN2 | |
| SCHEMBL3434282 | 0.75 | GRIN2D (0.46) | ALDH1A1SMN1; SMN2KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163746-B2 | Azolecarboxamide derivative | ASTELLAS PHARMA INC. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-8163746-B2 | Azolecarboxamide derivative | ASTELLAS PHARMA INC. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2009-11-19 | — | — | US | disclosed |
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | GPR17, NTRK1, TRPV1 | ALDH1A1 975/4885SMN1; SMN2 3601/4885OPRK1 237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.