Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 3/20 | 0.40 |
| ▸ | CDK9 | P50750 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2078054 | 0.92 | KDM4E (0.43) | CCNT1CDK9SMN1; SMN2KDM4ELMNA | |
| SCHEMBL3436524 | 0.86 | CCNT1 (0.42) | CCNT1CDK9SMN1; SMN2KDM4ELMNA | |
| SCHEMBL3435092 | 0.82 | CTSD (0.40) | CCNT1CDK9SMN1; SMN2KDM4ELMNA | |
| SCHEMBL3436022 | 0.80 | RAD52 (0.39) | SMN1; SMN2KDM4ELMNAMAPTALDH1A1 | |
| SCHEMBL3436391 | 0.77 | KDM4E (0.45) | CCNT1CDK9SMN1; SMN2KDM4ELMNA | |
| SCHEMBL3434233 | 0.74 | CDK9 (0.52) | CCNT1CDK9LMNASIGMAR1 | |
| SCHEMBL3434596 | 0.74 | CCNT1 (0.52) | CCNT1CDK9LMNASIGMAR1 | |
| SCHEMBL3435570 | 0.72 | CCNT1 (0.38) | CCNT1CDK9SMN1; SMN2KDM4ELMNA | |
| SCHEMBL3435686 | 0.72 | SIGMAR1 (0.42) | CCNT1CDK9SMN1; SMN2KDM4ELMNA | |
| SCHEMBL2078087 | 0.72 | CDK9 (0.41) | CCNT1CDK9SMN1; SMN2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163746-B2 | Azolecarboxamide derivative | ASTELLAS PHARMA INC. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | GPR17, NTRK1, TRPV1 | CCNT1 3047/4885CDK9 648/4885SMN1; SMN2 3601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.