Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 11/20 | 0.41 |
| ▸ | GPR6 | P46095 | 2/20 | 0.36 |
| ▸ | SMO | Q99835 | 3/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3436737 | 0.88 | OPRK1 (0.42) | OPRK1SMOCHRM4 | |
| SCHEMBL13999567 | 0.81 | OPRK1 (0.44) | OPRK1SMO | |
| SCHEMBL5540356 | 0.78 | ALDH1A1 (0.42) | — | |
| SCHEMBL3436734 | 0.76 | OPRK1 (0.43) | OPRK1GPR6SMOACACB | |
| SCHEMBL20135640 | 0.76 | SSTR2 (0.47) | OPRK1SMO | |
| SCHEMBL19049948 | 0.76 | CHRM4 (0.54) | GPR6CHRM4ACACB | |
| SCHEMBL5538573 | 0.74 | ALDH1A1 (0.46) | — | |
| SCHEMBL3557685 | 0.74 | KDM4E (0.52) | OPRK1 | |
| SCHEMBL19050015 | 0.74 | CHRM4 (0.42) | OPRK1SMOCHRM4 | |
| SCHEMBL12991619 | 0.73 | CNR2 (0.50) | OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163746-B2 | Azolecarboxamide derivative | ASTELLAS PHARMA INC. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | GPR17, NTRK1, TRPV1 | OPRK1 237/4885GPR6 292/4885SMO 1636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.