Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.37 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.37 |
| ▸ | SMO | Q99835 | 2/20 | 0.36 |
| ▸ | OXTR | P30559 | 2/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3436736 | 0.88 | OPRK1 (0.41) | OPRK1CHRM4SMO | |
| SCHEMBL3552903 | 0.80 | KMT2A (0.44) | OPRK1CHRM1TRPV1 | |
| SCHEMBL3436735 | 0.79 | OPRK1 (0.43) | OPRK1CHRM4CHRM1SMOCHRM2 | |
| SCHEMBL3552005 | 0.79 | OPRK1 (0.43) | OPRK1CHRM4CHRM1SMOTRPV1 | |
| SCHEMBL10278139 | 0.77 | KDM4E (0.50) | OPRK1CHRM1 | |
| SCHEMBL3436507 | 0.76 | KDM4E (0.51) | OPRK1CHRM1 | |
| SCHEMBL3436537 | 0.75 | ALDH1A1 (0.43) | CHRM4PARP1AVPR1ASCD | |
| SCHEMBL3555340 | 0.74 | MAPT (0.56) | — | |
| SCHEMBL21262656 | 0.72 | KDM4E (0.47) | CHRM1 | |
| SCHEMBL5540356 | 0.71 | ALDH1A1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163746-B2 | Azolecarboxamide derivative | ASTELLAS PHARMA INC. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | GPR17, NTRK1, TRPV1 | OPRK1 237/4885CHRM4 587/4885CHRM1 555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.