Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 5/20 | 0.53 |
| ▸ | CA2 | P00918 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14326995 | 0.91 | CA2 (0.55) | GAAPOLBCA1CA2NPC1 | |
| SCHEMBL19301016 | 0.87 | GAA (0.48) | GAAPOLBCA1CA2NPC1 | |
| SCHEMBL22996211 | 0.87 | CA1 (0.54) | GAAPOLBCA1CA2NPC1 | |
| SCHEMBL22996206 | 0.87 | CA1 (0.54) | GAAPOLBCA1CA2TDP1 | |
| SCHEMBL7465537 | 0.87 | ESRRG (0.58) | GAAPOLBCA1CA2TDP1 | |
| SCHEMBL21077910 | 0.85 | DRD2 (0.55) | GAACA1CA2TDP1SIGMAR1 | |
| SCHEMBL8381122 | 0.85 | CA1 (0.53) | GAAPOLBCA1CA2TDP1 | |
| SCHEMBL4039313 | 0.85 | CA1 (0.56) | GAAPOLBCA1CA2TDP1 | |
| SCHEMBL2551512 | 0.85 | CA1 (0.53) | GAAPOLBCA1CA2NPC1 | |
| SCHEMBL6833896 | 0.85 | CA1 (0.53) | GAAPOLBCA1CA2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015142001-A2 | COMPOUND HAVING CARDIOTONIC ACTIVITY AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING HEART FAILURE, CONTAINING SAME | 충남대학교산학협력단 | 2015-09-24 | — | — | WO | disclosed |
| US-7807720-B2 | Hydroxamic acid derivatives of 3-phenyl propionic acids useful as therapeutic agents for treating anthrax poisoning | PANTHERA BIOPHARMA, LLC (US) | 2010-10-05 | — | — | US | disclosed |
| US-7807720-B2 | Hydroxamic acid derivatives of 3-phenyl propionic acids useful as therapeutic agents for treating anthrax poisoning | PANTHERA BIOPHARMA, LLC (US) | 2010-10-05 | — | — | US | disclosed |
| WO-2008147480-A2 | HYDROXAMIC ACID DERIVATIVES OF 3-PHENYL PROPIONIC ACIDS USEFUL AS THRAPEUTIC AGENTS FOR TREATING ANTHRAX POISONING | PANTHERA BIOPHARNA, LLC. (US) | 2008-12-04 | — | — | WO | disclosed |
| WO-2008147480-A2 | HYDROXAMIC ACID DERIVATIVES OF 3-PHENYL PROPIONIC ACIDS USEFUL AS THRAPEUTIC AGENTS FOR TREATING ANTHRAX POISONING | PANTHERA BIOPHARNA, LLC. (US) | 2008-12-04 | — | — | WO | disclosed |
| US-20080188566-A1 | Hydroxamic acid derivatives of 3-Phenyl propionic acids useful as therapeutic agents for treating anthrax poisoning | PAN THERA BIOPHARMA,LLC | 2008-08-07 | — | — | US | disclosed |
| US-20080188566-A1 | Hydroxamic acid derivatives of 3-Phenyl propionic acids useful as therapeutic agents for treating anthrax poisoning | PAN THERA BIOPHARMA,LLC | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188566-A1 | Hydroxamic acid derivatives of 3-Phenyl propionic acids useful as therapeutic agents for treating anthrax poisoning | ANTXR2, PAOX, AGXT | GAA 331/4885POLB 3056/4885CA1 26/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.