Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25048712 | 0.89 | MAPT (0.50) | MAPTGAAPOLBLMNAALDH1A1 | |
| SCHEMBL3438533 | 0.80 | MAPT (0.50) | MAPTGAAPOLBLMNAALDH1A1 | |
| SCHEMBL8133890 | 0.79 | — | — | |
| SCHEMBL498606 | 0.79 | MAPT (0.47) | MAPTGAAPOLBLMNAALDH1A1 | |
| SCHEMBL1781122 | 0.78 | MAPT (0.57) | MAPTGAAPOLBLMNAALDH1A1 | |
| SCHEMBL663162 | 0.77 | MAPT (0.46) | MAPTGAAPOLBLMNAALDH1A1 | |
| SCHEMBL930295 | 0.77 | MAPT (0.46) | MAPTGAAPOLBLMNAALDH1A1 | |
| SCHEMBL7122480 | 0.75 | MAPT (0.44) | MAPTGAAPOLBLMNAALDH1A1 | |
| SCHEMBL497608 | 0.74 | — | — | |
| Formic Acid SCHEMBL27498736 | 0.73 | POLB (0.47) | MAPTGAAPOLBLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110117270-B | Preparation method of 3- (thiophene-2-yl) cyclohexanone framework compound | 山西大学 | 2021-07-27 | — | — | CN | claimed |
| CN-110117270-B | Preparation method of 3- (thiophene-2-yl) cyclohexanone framework compound | 山西大学 | 2021-07-27 | — | — | CN | disclosed |
| CN-110117270-B | Preparation method of 3- (thiophene-2-yl) cyclohexanone framework compound | 山西大学 | 2021-07-27 | — | — | CN | disclosed |
| CN-110117270-B | Preparation method of 3- (thiophene-2-yl) cyclohexanone framework compound | 山西大学 | 2021-07-27 | — | — | CN | disclosed |
| US-7807856-B2 | Process for production of 2-Benzylphenol compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-10-05 | — | — | US | disclosed |
| US-20080194882-A1 | Process For Production of 2-Benzylphenol Compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2008-08-14 | — | — | US | disclosed |
| EP-1810957-A1 | METHOD FOR PRODUCING 2-BENZYLPHENOL COMPOUND | Ihara Chemical Industry Co., Ltd. (JP) | 2007-07-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194882-A1 | Process For Production of 2-Benzylphenol Compound | CYP1B1, CYP4B1, CYP1A1 | MAPT 4506/4885GAA 3701/4885POLB 2816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.