SCHEMBL930295

SCHEMBL930295

c1csc(C2CCCCCC2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.46
POLB P06746 1/20 0.46
GAA P10253 1/20 0.46
HPGD P15428 4/20 0.42
ALDH1A1 P00352 4/20 0.42
RAB9A P51151 3/20 0.42
TSHR P16473 3/20 0.42
NPC1 O15118 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C19 P33261 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
LMNA P02545 2/20 0.39
KDM4E B2RXH2 1/20 0.39
HTT P42858 1/20 0.39
HSD17B10 Q99714 1/20 0.39
RORC P51449 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL663162 1.00 MAPT (0.46) MAPTPOLBGAAHPGDALDH1A1
SCHEMBL7122480 0.98 MAPT (0.44) MAPTPOLBGAAHPGDALDH1A1
SCHEMBL498606 0.98 MAPT (0.47) MAPTPOLBGAAHPGDALDH1A1
SCHEMBL8133890 0.93
SCHEMBL28794480 0.89 MAPT (0.42) MAPTPOLBGAAHPGDALDH1A1
SCHEMBL497608 0.87
Acetic Acid SCHEMBL11173187 0.87 BRD4 (0.47) MAPTPOLBGAAHPGDALDH1A1
SCHEMBL28657261 0.86 MAPT (0.40) MAPTPOLBGAAHPGDALDH1A1
Hydrochloric Acid SCHEMBL11286601 0.85
Methylamine SCHEMBL28610020 0.81 MAPT (0.46) MAPTPOLBGAAHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070225318-A1 Pyrazole Compounds Useful In The Treatment Of Inflammation BIOLIPOX AB (SE) 2007-09-27 US claimed
CN-112673715-B Electronic component and method for manufacturing electronic component 株式会社力森诺科 2025-03-07 CN disclosed
CN-119156892-A Method for manufacturing substrate with conductive via hole and method for manufacturing wiring substrate with conductive via hole 株式会社力森诺科 2024-12-17 CN disclosed
CN-119096706-A Method for manufacturing substrate with conductive through hole, substrate with conductive through hole and metal paste 株式会社力森诺科 2024-12-06 CN disclosed
CN-111230125-B Copper paste for bonding, method for producing bonded body, and method for producing semiconductor device 株式会社力森诺科 2024-11-26 CN disclosed
CN-111283206-B Copper paste for bonding, method for producing bonded body, and method for producing semiconductor device 株式会社力森诺科 2024-11-26 CN disclosed
CN-111360270-B Bonded body and semiconductor device 株式会社力森诺科 2024-11-22 CN disclosed
US-12076715-B1 Synthesis and characterization of air-stable iron-based catalysts for Suzuki-Miyaura cross-coupling reactions of alkyl halides and aryl boronic esters THE TRUSTEES OF BOSTON COLLEGE (MA) 2024-09-03 US disclosed
CN-117916038-A Metal paste for bonding, bonded body, and method for producing same 株式会社力森诺科 2024-04-19 CN disclosed
CN-117897244-A Metal paste for bonding, bonded body, and method for producing same 株式会社力森诺科 2024-04-16 CN disclosed
US-20070225318-A1 Pyrazole Compounds Useful In The Treatment Of Inflammation BIOLIPOX AB (SE) 2007-09-27 US disclosed
EP-1794145-A1 PYRAZOLE COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATION Biolipox AB (SE) 2007-06-13 EP disclosed
EP-0837052-B1 BICYCLIC AMINO DERIVATIVES AND PGD 2 ANTAGONIST CONTAINING THE SAME SHIONOGI & CO (JP) 2006-08-23 EP disclosed
WO-2006032851-A1 PYRAZOLE COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATION BIOLIPOX AB (SE) 2006-03-30 WO disclosed
CN-1134411-C Bicyclic amino derivatives and PGDZ antagonist containing same C&C��ҩ�о��� 2004-01-14 CN disclosed
US-6172113-B1 Bicyclic amino derivatives and PGD2 antagonist containing the same SHIONOGI & CO., LTD. (JP) 2001-01-09 US disclosed
EP-1049689-A1 4-(2-KETO-1-BENZIMIDAZOLINYL)PIPERIDINE COMPOUNDS AS ORL1-RECEPTOR AGONISTS PFIZER INC. (US) 2000-11-08 EP disclosed
WO-1999036421-A1 4-(2-KETO-1-BENZIMIDAZOLINYL)PIPERIDINE COMPOUNDS AS ORL1-RECEPTOR AGONISTS PFIZER PHARMACEUTICALS INC. (JP) 1999-07-22 WO disclosed
EP-0577712-A1 FUNGICIDAL 4-THIOXOOXAZOLIDIN-2-ONES AND 4-IMINOOXAZOLINDIN-2-ONES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1994-01-12 EP disclosed
WO-1992016515-A1 FUNGICIDAL 4-THIOXOOXAZOLIDIN-2-ONES AND 4-IMINOOXAZOLINDIN-2-ONES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-10-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070225318-A1 Pyrazole Compounds Useful In The Treatment Of Inflammation ALOX15, ALOX15B, ALOX12 MAPT 4420/4885POLB 2208/4885GAA 2871/4885
US-12076715-B1 Synthesis and characterization of air-stable iron-based catalysts for Suzuki-Miyaura cross-coupling reactions of alkyl halides and aryl boronic esters NBAS, BLVRB, TFRC MAPT 4211/4885POLB 1547/4885GAA 1801/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.