Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25048712 | 0.90 | MAPT (0.50) | MAPTPOLBGAAALDH1A1MEN1 | |
| SCHEMBL497608 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL11286601 | 0.80 | — | — | |
| SCHEMBL3438176 | 0.80 | MAPT (0.47) | MAPTPOLBGAAALDH1A1MEN1 | |
| SCHEMBL498606 | 0.78 | MAPT (0.47) | MAPTPOLBGAAALDH1A1MEN1 | |
| SCHEMBL8133890 | 0.78 | — | — | |
| SCHEMBL1781122 | 0.78 | MAPT (0.57) | MAPTPOLBGAAALDH1A1MEN1 | |
| Methylamine SCHEMBL28610020 | 0.76 | MAPT (0.46) | MAPTPOLBGAAALDH1A1MEN1 | |
| SCHEMBL663162 | 0.76 | MAPT (0.46) | MAPTPOLBGAAALDH1A1MEN1 | |
| Cyanide SCHEMBL27408712 | 0.76 | MAPT (0.46) | MAPTPOLBGAAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7807856-B2 | Process for production of 2-Benzylphenol compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-10-05 | — | — | US | disclosed |
| US-7727979-B2 | Guanidine derivatives and their use as neuropeptide FF receptor antagonists | ACTELION PHARMACEUTICALS LTD. (CH) | 2010-06-01 | — | — | US | disclosed |
| US-20080194882-A1 | Process For Production of 2-Benzylphenol Compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2008-08-14 | — | — | US | disclosed |
| EP-1810957-A1 | METHOD FOR PRODUCING 2-BENZYLPHENOL COMPOUND | Ihara Chemical Industry Co., Ltd. (JP) | 2007-07-25 | — | — | EP | disclosed |
| US-20060194788-A1 | Guanidine derivatives and their use as neuropeptide ff receptor antagonists | ACTELION PHARMACEUTICALS LTD. (CH) | 2006-08-31 | — | — | US | disclosed |
| EP-1608662-A1 | GUANIDINE DERIVATIVES AND USE THEREOF AS NEUROPEPTIDE FF RECEPTOR ANTAGONISTS | Actelion Pharmaceuticals Ltd. (CH) | 2005-12-28 | — | — | EP | disclosed |
| WO-2004083218-A1 | GUANIDINE DERIVATIVES AND USE THEREOF AS NEUROPEPTIDE FF RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2004-09-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194882-A1 | Process For Production of 2-Benzylphenol Compound | CYP1B1, CYP4B1, CYP1A1 | MAPT 4506/4885POLB 2816/4885GAA 3701/4885 |
| US-20060194788-A1 | Guanidine derivatives and their use as neuropeptide ff receptor antagonists | NPFFR1, OGFR, NPFFR2 | MAPT 1891/4885POLB 3270/4885GAA 1530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.